Características de los debuts diabéticos en los niños ingresados en un hospital terciario durante diez años / Characteristics of diabetic debuts in children admitted to a tertiary hospital for ten years

Introducción. La diabetes mellitus tipo 1 constituye unade las patologías crónicas más frecuentes en la infancia. Suincidencia está sufriendo un incremento en los últimos años.Objetivo. Describir y analizar las características epidemiológicas, clínicas, analíticas y terapéuticas en el momentodel debut de la enfermedad, comparándolas entre gruposde edad de los pacientes que debutan con DM1 en nuestraprovincia.Pacientes y métodos. Estudio observacional retrospectivo mediante revisión de historias clínicas de pacientesmenores de 14 años con debut de diabetes tipo 1 entre 2007y 2017 en un hospital de tercer nivel. La muestra se dividiópor edades en tres grupos (0-4 años, 5-9 años,10-14 años).Resultados. Se recogieron 64 pacientes con edad mediade 8,15 años (DE 3,41), el 48,4% entre 5-9 años. No se hallarondiferencias de sexo ni patrón estacional, aunque los pacientesde menor edad debutaron más frecuentemente en invierno.No se observó aumento en la incidencia con el tiempo nidiferencias en los síntomas entre grupos. Debutaron concetoacidosis diabética el 36%, fundamentalmente leves.Encontramos un porcentaje menor de anticuerpos IAA yantiGAD de lo esperado y mayor frecuencia de antecedentesfamiliares positivos. Se observó correlación lineal positivaentre las cifras de bicarbonato y cuerpos cetónicos en sangrey las necesidades de insulina por kg de peso (p 0,025 y p0,05, respectivamente). Los niños de menor edad presentanniveles de HbA1c más bajos al inicio de la enfermedad.Conclusiones. En nuestro medio no se está produciendoun aumento en el número de casos de esta enfermedad, aunque los mismos se concentran a menor edad de la esperada (AU)

Introduction. Type 1 diabetes mellitus is one of the mostfrequent chronic pathologies in childhood. Its incidence hasincreased in the last years.Objective. To analyze the epidemiological, clinical,analytical and therapeutic characteristics at the time of thedisease’s onset, and to compare them between age groupsof those patients with Diabetes mellitus type 1 in our region.Patients and methods. Retrospective observational studyby reviewing the medical records of patients under 14 yearsof age with onset of type 1 diabetes between 2007 and 2017in a tertiary-level hospital. The sample was divided by ageinto three groups (0-4 years, 5-9 years,10-14 years).Results. 64 patients were studied, the mean age was8.15 years (SD 3.41), 48.4% of them between 5-9 years. Nodifferences in sex or seasonal pattern were found, althoughyounger children became ill more frequently in winter. There was no increase in incidence over time ordifferencesin symptoms between groups. 36% debuted with diabeticketoacidosis, mainly mild. We found a lower percentage ofIAA and antiGAD antibodies than expected and a higherfrequency of positive family history. A positive linear correlation was observed between the levels of bicarbonateand ketone bodies in blood and the insulin needs per kg ofweight (p 0.025 and p 0.05 respectively). Younger childrenhave lower HbA1c levels at the beginning of the disease.Conclusions. In our centre there is not an increase in thenumber of cases of this disease, although we found morecases at a younger age than expected. (AU)

Complicaciones neurológicas asociadas a infección por virus Influenza / Neurological complications associated to Influenza virus infection

Objetivos. Revisar las complicaciones neurológicas por virus Influenza y las características clínico-epidemiológicas. Material y métodos. Estudio descriptivo, observacional, retrospectivo mediante revisión de historias clínicas de niños ingresados con complicaciones neurológicas por virus Influenza entre enero de 2013 y febrero de 2019. Resultados. Se incluyeron 14 pacientes (11 varones), el 85,7% con infección por Influenza A. La mediana de edad fue 2 años (3 meses-11 años). Tenían antecedentes neurológicos 3 (convulsiones febriles). El 64,3% asociaba fiebre, con una duración media de 2,15±2,3 días. Los síntomas neurológicos se presentaron el primer día de fiebre en 7 pacientes. La clínica neurológica fue: convulsión (11/14): 8 febriles y 3 afebriles, encefalopatía (1), cefalea (1) y meningismo (1). En cuanto a las convulsiones febriles, la mediana de edad fue de 3 años. Cuatro tenían más de 6 años. En el 75% la convulsión febril se produjo el primer día de fiebre y en 5 recurrieron en 24 horas. Se aisló Influenza A en el 82% de pacientes con convulsiones. Recibieron tratamiento con oseltamivir 6 pacientes. Ninguno ha presentado secuelas. Conclusiones. En nuestra muestra, el virus más frecuente fue el virus Influenza A, produciendo este la mayoría de las complicaciones a nivel neurológico, especialmente en varones en edad escolar. La complicación más frecuente fue la convulsión, la mayoría convulsiones febriles, aunque hasta en un 28% se presentó a una edad atípica. Al igual que en otras series, el virus Influenza se puede asociar a complicaciones graves como rombencefalitis. En la mayoría de los pacientes los exámenes complementarios fueron normales (AU)

Objectives. To review neurological complications due to influenza virus and clinical-epidemiological characteristics. Material and methods. Descriptive, observational, retrospective study by reviewing clinical records of children admitted with neurological complications due to influenza virus between January 2013-February 2019. Results. Fourteen patients were included (11 males), 85.7% with infection by Influenza A. Median age was 2 years (3 months-11 years). They had neurological history 3 (febrile seizures). The 64.3% associated fever, with a mean duration of 2.15±2.3 days. Neurological symptoms occurred on the first day of fever in 7 patients. The neurological clinic was: seizure (11/14): 8 febrile and 3 afebrile, encephalopathy (1), headache (1) and meningism (1). As for febrile seizures, the median age was 3 years. Four were older than 6 years old. In 75% the febrile seizure occurred on the first day of fever and in 5 they recurred within 24 hours. Influenza A was isolated in 82% of patients with seizures. Six patients were treated with oseltamivir. None of them presented sequelae. Conclusions. In our sample, the most frequent virus was the Influenza A virus, producing most of the neurological complications, especially in school-age males. The most frequent complication was the seizure, mostly febrile seizures; although up to 28% presented at an atypical age. As in other series, the Influenza virus can be associated to serious complications such as rhombencephalitis. In most of the patients, the complementary exams were normal (AU)

Buscando precisión en el montaje en articulador / Looking for precision in articulator mounting

Se presenta una técnica de montaje de precisión, de fácil ejecución y al alcance del odontólogo y del técnico de laboratorio, destinada a brindar un mejor resultado clínico de los procedimientos restauradores, tanto protéticos como ortodóncicos

We present a technique for precision assembly, easy to perform and reach for the dentist and lab technician, aimed at providing a better clinical outcome of both prosthetic and orthodontics restorative procedures.

Good Short-Term Outcome of Kangaroo Mother care in Low Birth Weight Infants in a Rural South African Hospital

Objective: The aim of the study was to determine the outcome of kangaroo mother care (KMC) in low birth weight infants at a community hospital. Methods : This descriptive study included 87 mothers and their low birth weight infants who were in a stable condition and eligible for KMC at Dr JS Moroka Hospital; Thaba Nchu. The infants were assessed four times: at birth; twice during hospitalisation; and a week after discharge. Infants received breast milk exclusively.Results : Regarding the mothers' obstetric history (n=87); gravidity ranged from 1 to 7 (median 3); with a 43 incidence of miscarriage. The median birth weight of the infants (n=87) was 1.5 kg (first assessment); the discharge weight (third assessment) was 1.8 kg; and a week after discharge (fourth assessment) it was 2.2 kg. Initially the infants lost weight significantly from birth to the second assessment (95 CI for median decrease [-0.02; -0.01]); but significantly gained weight from the second to the third (95 CI for median decrease [0.27; 0.33]) and from the third to the fourth assessment (95 CI for median decrease [0.32; 0.45]). Approximately half (49) of the infants had developed jaundice by the time of second assessment. These babies had a significantly lower birth weight [0.12;0.30]. Conclusion : Our findings confirm that infants with a low birth weight treated with KMC can have a good growth pattern; and exclusive breast milk is sufficient to guarantee such growth. Kangaroo mother care is a safe method for stable infants with a low birth weight in a community hospital

Recurrent hemoptysis following a systemic-to-pulmonary anastomosis in a child with a complex congenital cardiomyopathy.

A 14-year-old boy with a history of congenital cardiopathy is presented. At age 4, a left systemic-to-pulmonary fistula was performed, using a tubular prosthesis to anastomose the left subclavian artery to the left pulmonary artery. Following this procedure, he developed recurrent episodes of hemoptysis, cough, and left upper lobe consolidation. Treatment resulted in clinical but no radiologic resolution. At age 6, a new right systemic-to-pulmonary anastomosis was needed, as the left one was no longer functioning. After placement of the second shunt, the hemoptysis disappeared. At age 14, flexible bronchoscopy revealed a foreign body granuloma at the left secondary carina. Rigid bronchoscopy and laser photoresection showed it to be the left vascular prosthesis, placed 10 years before. Surgery failed to remove it.

Effectiveness of endoscopic sphincterotomy in complicated hepatic hydatid disease.

BACKGROUND: The aim of this study was to evaluate the results of endoscopic sphincterotomy in patients with hepatic hydatid cysts that have ruptured into the biliary tract. METHODS: Over a 10-year period, 25 patients (11 men, 14 women, mean age 60 years) underwent treatment; 13 with no prior surgery were treated for biliary obstruction. Postoperative treatment was undertaken in 12 cases because of persistent drainage (8), duct obstruction (3), and postoperative pancreatitis (1). RESULTS: In patients who had not undergone previous surgery, cholangiographic findings were hydatid vesicles in the biliary tract (6), dilation of the biliary tract (3), biliary fistula (2), distal stenosis (1), and purulent bile content after sphincterotomy (1). In all of these cases, sphincterotomy resolved duct obstruction with no complications. All patients with persistent postoperative drainage had a fistula tract between the biliary duct and the cavity, which was resolved by endoscopic treatment in all 8. The 3 patients with postoperative biliary obstruction had hydatid vesicles in the biliary tract, one with a long stenosis resembling sclerosing cholangitis, whereas the patient with postoperative pancreatitis had a distal stenosis. Satisfactory results were obtained with endoscopic sphincterotomy, although 1 patient required a biliary prosthesis. CONCLUSION: Endoscopic sphincterotomy resolves biliary obstruction and postoperative fistulae in most patients with hepatic hydatid cysts that have ruptured into the biliary tract. In some cases, a biliary prosthesis may be required.