RESUMO
CASE REPORT: A 33-year-old woman with superficial and deep bilateral corneal vascularization and keratoconjunctivitis sicca, keratoerythema and neurosensory deafness, was diagnosed with keratitis-ichthyosis-deafness (KID) syndrome. DISCUSSION: KID syndrome is a congenital ectodermal dysplasia characterized by the association of vascularizing keratitis, hyperkeratotic skin lesions and sensorineural hearing loss. Recently, limbal stem cell deficiency was recognized as a possible major pathogenetic factor.
Assuntos
Surdez/diagnóstico , Oftalmopatias/diagnóstico , Ictiose/diagnóstico , Ceratite/diagnóstico , Adulto , Surdez/congênito , Oftalmopatias/tratamento farmacológico , Oftalmopatias/genética , Feminino , Perda Auditiva Neurossensorial/congênito , Perda Auditiva Neurossensorial/diagnóstico , Humanos , Ictiose/tratamento farmacológico , Ictiose/genética , Ceratite/congênito , Ceratite/tratamento farmacológico , Mutação , Soluções Oftálmicas/uso terapêutico , Síndrome , Acuidade VisualRESUMO
Caso clínico: Mujer de 33 años con neovascularizacióncorneal bilateral superficial y profunda yqueratopatía punteada superficial de distribucióndifusa, queratoeritema y sordera neurosensorial,que es diagnosticada de síndrome KID.Discusión: El síndrome KID es una displasia congénitaectodérmica caracterizada por la asociaciónde queratitis vascularizante, lesiones cutáneashiperqueratósicas y sordera neurosensorial. Recientemente,la deficiencia de stem cell limbares ha sidoreconocida como posible factor patogenético clave
Case report: A 33-year-old woman with superficial ;;and deep bilateral corneal vascularization and ;;keratoconjunctivitis sicca, keratoerythema and neurosensory ;;deafness, was diagnosed with keratitisichthyosis- ;;deafness (KID) syndrome. ;;Discussion: KID syndrome is a congenital ectodermal ;;dysplasia characterized by the association of ;;vascularizing keratitis, hyperkeratotic skin lesions ;;and sensorineural hearing loss. Recently, limbal ;;stem cell deficiency was recognized as a possible ;;major pathogenetic factor
Assuntos
Feminino , Adulto , Humanos , Neovascularização da Córnea/patologia , Ceratite Dendrítica/patologia , Ictiose , Surdez , Conexinas/isolamento & purificação , Hiperceratose Epidermolítica , Células-TroncoRESUMO
CASE REPORT: Case 1: An 82-year-old man who underwent an uncomplicated phacoemulsification and IOL implantation (Tecnis Z 9000 lens) in his right eye under topical anaesthesia. Surgery lasted 14 minutes. Case 2: A 60-year-old woman with bilateral advanced primary open angle glaucoma who underwent an uncomplicated phacoemulsification and IOL implantation (Tecnis Z 9000 lens) in her right eye under peribulbar anaesthesia. Surgery lasted 36 minutes. One month after surgery both patients noted a para-central scotoma and impaired vision. Fluorescein angiography in both cases revealed retinal pigment epithelial changes compatible with intra-operative light-induced maculopathy. DISCUSSION: Light-induced maculopathy has been reported following cataract surgery. Whether physical properties of these new polysiloxane lenses contribute to retinal susceptibility to phototoxicity under certain light conditions needs to be elucidated.
Assuntos
Luz/efeitos adversos , Facoemulsificação/efeitos adversos , Doenças Retinianas/etiologia , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
CLINICAL CASE: We present a case of a 40-years-old woman with an acute posterior multifocal placoid pigment epitheliopathy (APMPPE) associated with recent instauration hyperthyroidism symptoms. A Graves' disease was diagnosed and the patient was initially controlled with antithyroid drugs. The epitheliopathy evolution was relatively favourable without relapse. Two years later a thyroidectomy was performed. DISCUSSION: We have not found in the literature any APMPPE case associated with Graves' disease. We only found an APMPPE case associated with a subacute thyroiditis. Little is known about the APMPPE causes, it could be that placoid epitheliopathy and Graves' disease had a common autoimmune origin. We can not forget that our finding could be only a matter of chance.
Assuntos
Doença de Graves/complicações , Epitélio Pigmentado Ocular/patologia , Doenças Retinianas/etiologia , Tireoidite Subaguda/complicações , Doença Aguda , Adulto , Antitireóideos/uso terapêutico , Corioide/irrigação sanguínea , Terapia Combinada , Feminino , Angiofluoresceinografia , Doença de Graves/tratamento farmacológico , Doença de Graves/cirurgia , Terapia de Reposição Hormonal , Humanos , Isquemia/complicações , Metimazol/uso terapêutico , Epitélio Pigmentado Ocular/diagnóstico por imagem , Radiografia , Doenças Retinianas/diagnóstico por imagem , Tireoidectomia , Tireoidite Subaguda/tratamento farmacológico , Tireoidite Subaguda/cirurgia , Tiroxina/uso terapêuticoRESUMO
Caso clínico: Paciente mujer de 40 años de edad que presentó una epiteliopatía pigmentaria placoide multifocal posterior aguda (EPPMPA) asociada a un cuadro de hipertiroidismo de instauración reciente. La paciente fue diagnosticada de enfermedad de Graves y fue controlada inicialmente con tratamiento antitiroideo. La epiteliopatía evolucionó de forma relativamente favorable sin recidivas. A los dos años se practicó tiroidectomía subtotal. Discusión: No hemos encontrado en la bibliografía ningún caso de EPPMPA asociada a enfermedad de Graves. Sólo hallamos un caso de EPPMPA asociada a una tiroiditis subaguda. Poco se conoce sobre las causas de la EPPMPA, podría ser que la epiteliopatía placoide y la enfermedad de Graves tuvieran un origen autoinmune común. No podemos descartar la posibilidad de que nuestro hallazgo sea sólo casual (AU)
