Tumor intraabdominal desmoplásico de células pequeñas y redondas. Revisión de la literatura a propósito de un caso con estudio citológico, histopatológico, inmunohistoquímico y molecular / No disponible

Propósito: Revisar los hallazgos citohistopatológicos,inmunohistoquímicos y moleculares del tumorde células pequeñas redondas (DSRCT).Material y métodos: Varón de 18 años conmasa intraabdominal epigástrica.Resultados: Tumoración constituida por unaproliferación en nidos y difusa de células pequeñasindiferenciadas sobre estroma desmoplásico, conformación de rosetas, inmunorreactivas para citoqueratinas,vimentina, desmina y enolasa y la fracciónWT1 de la proteína EWS/WT1. El estudio moleculardemostró la traslocación t(11;22)(p13;q12).Conclusiones: La formación de rosetas y lasáreas sólidas han sido descritas en otros casos deDSRCT. El producto quimérico puede detectarse medianteRT-PCR, Southern-blot, Western-blot e inmunohistoquímica.El estudio citológico está especialmenteindicado en el diagnóstico de recidivas. Eldiagnóstico diferencial debe incluir el grupo de tumoresindiferenciados de células pequeñas y redondas

Purpose: To review the cyto-histopathological, immunohistochemical and molecular characteristicsof small round cell desmoplastic tumor (DSRCT).Material and methods: A 18 year old malewith an intraabdominal epigastric mass.Results: The tumor consisted of nests andmasses of undifferentiated small round cellsembedded in a desmoplastic stroma, with areas ofrosette formation immuno-reactive to cytokeratins,vimentin, desmin, enolase, and WT1 fraction of theEWS/WT1 fusion protein transcript. The molecularstudy demonstrated the existence of the translocationt(11;22)(p13;q12).Conclusions: The solid areas and rosetteformation have been described in other cases ofDSRCT. The chimeric transcription product can bedetected by RT-PCR, Southern-blot, Western-blot,and immunohistochemistry. Cytology is especiallyuseful in recurrences. The differential diagnosisshould be made with the small round undifferented cell tumors group (AU)

[Anisakidosis of the colon as a cause of acute abdomen]. / Anisakidosis del colon como causa de abdomen agudo.

We report a case of acute abdomen caused by the invasion of the ascending colon by larvae of Anisakis simplex in a 57 year-old-woman whose initial symptoms were colic abdominal pain, diarrhea and fever. The diagnosis was done by the histological study of the surgical specimen in which two parasites were morphologically identified in the submucosa. Although a causal relationship of the disease with the ingestion of crude fish could not be established initially, there were antecedents of ingestion of anchovy in vinegar (Engraulis encrasicholus) and dyspeptic symptoms for several months.