1.
Z Naturforsch C J Biosci
; 55(3-4): 292-4, 2000.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10817222
RESUMO
1-(4-Morpholinomethyl)-tetrahydro-2(1H)-pyrimidinone (mopyridone) exhibited a marked activity against rubella virus (Judith and RA27/3 strains), a MIC50 value of 0.9 microM and selectivity ratio of 557.7 been found in the case of Judith strain. These data, in addition to the previous ones about its anti-alphavirus effects suggest the compound to be considered as a broad spectrum inhibitor of togavirus replication.