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1.
Toxicol Lett ; 319: 111-118, 2020 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-31715245

RESUMO

INTRODUCTION: Silver ion has strong antimicrobial properties and is used in a number of wound dressings. In burn models, silver-nylon dressings produce elevated silver levels in the wound along with minimal systemic effect. We evaluated systemic toxicity in a non-burn wound model to see if a similar pattern of silver ion distribution would occur. METHODS: Eight deep partial-thickness wounds each were created on the dorsum of 40 Gottingen minipigs using a Er-YAG Laser. Half were treated with a 21-day course of silver-nylon dressings (Silverlon®) and half were treated with moist gauze dressings. Wound, blood, liver and kidney silver levels, along with blood chemistry and hematology data were obtained at appropriate intervals. RESULTS: All wounds healed well with healing enhanced by silver-nylon dressings. Silver ion was demonstrable in all wounds treated with silver-nylon at day 21 and after 14 days of no further treatment. Silver ion was not detected in blood, liver or kidney of any animal treated with silver-nylon or control dressings. Liver and kidney function remained normal in all animals. CONCLUSION: A 21-day application of silver-nylon dressings to a non-burn dermal wound produces no systemic or local toxicity in Gottingen minipigs.


Assuntos
Anti-Infecciosos/toxicidade , Bandagens , Prata/toxicidade , Pele/lesões , Animais , Feminino , Masculino , Nylons , Prata/farmacocinética , Suínos , Porco Miniatura , Cicatrização
2.
World Neurosurg ; 133: e149-e155, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31476473

RESUMO

BACKGROUND: Although new imaging tools have been developed for the detection of smaller aneurysms, angiographically negative microaneurysms are still encountered during cerebral microsurgery. Currently, only limited information regarding incidence and efficacy of treatment of these microaneurysms is available. METHODS: We investigated the incidence and treatment of incidental microaneurysms (IMAs) in the last 5 years. IMAs are unidentifiable and invisible on preoperative angiography, but are detected during microvascular surgery. The inclusion criteria were aneurysm cases treated with microsurgery via transsylvian approaches, and those undergoing preoperative digital subtraction angiography. RESULTS: This study enrolled 484 surgical cases (248 cases of subarachnoid hemorrhage and 236 cases of unruptured aneurysms) in 460 patients, and 33 tiny aneurysms were found in 31 operative cases (6.4% incidence per operation). The most typical type was located on another branching site of the middle cerebral artery found during neck clipping of the middle cerebral artery bifurcation aneurysm. A patient with multiple aneurysms presented a statistically significant risk (375/78 vs. 15/16; P < 0.001) of IMA identification. IMAs were treated by clipping and wrapping in 18 and 15 cases, respectively, without complications. CONCLUSIONS: This study revealed a 6.4% incidence of IMAs; however, this could be underestimated because of the limited range of inspection. Early detection of an IMA through careful inspection during microvascular surgery could be beneficial, especially in patients with multiple aneurysms.


Assuntos
Aneurisma Intracraniano/epidemiologia , Microaneurisma/epidemiologia , Microcirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Aneurisma Roto/cirurgia , Bandagens , Angiografia Cerebral , Comorbidade , Constrição , Craniotomia , Feminino , Humanos , Incidência , Achados Incidentais , Aneurisma Intracraniano/diagnóstico por imagem , Aneurisma Intracraniano/cirurgia , Aneurisma Intracraniano/terapia , Masculino , Microaneurisma/diagnóstico por imagem , Microaneurisma/cirurgia , Microaneurisma/terapia , Pessoa de Meia-Idade
3.
Carbohydr Polym ; 227: 115360, 2020 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-31590866

RESUMO

Some applications, in particular, wound dressings, require significant water holding capability: hydrogels formed from Basil seed mucilage (BSM) are non-toxic natural substances and exhibit the needed water holding capacity. However, the sponges have low dimensional stability and easily degrade in aqueous media. We overcame this drawback by crosslinking with borax. To provide antibacterial activity, zinc oxide nanoparticles (ZnO-NP) were added. With 10-20 wt% added borax and ZnO-NP, all key properties improved: dimensional stability, water retention capacity (31 to 41%), stress at maximum load (2.6 to 6.6 MPa), Young's modulus (74 to 113 MPa) and strain (28 to 54%). An interconnecting system of pores with well distributed ZnO-NP was observed from scanning electron microscope. In addition, higher borax and ZnO-NP loadings slightly decreased porosity (92% to 73%) and swelling (109 to 56). Moreover, antibacterial activity and cytotoxicity of BSM hydrogel sponge were also examined.


Assuntos
Antibacterianos/química , Bandagens , Boratos/química , Sistemas de Liberação de Medicamentos , Nanocompostos/química , Mucilagem Vegetal/química , Óxido de Zinco/química , Linhagem Celular , Sobrevivência Celular , Escherichia coli/crescimento & desenvolvimento , Humanos , Ocimum basilicum , Sementes , Staphylococcus aureus/crescimento & desenvolvimento
4.
Carbohydr Polym ; 227: 115296, 2020 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-31590872

RESUMO

Cutaneous chronic wounds are characterized by an impaired wound healing which may lead to infection. To surmount this problem, a novel quaternary ammonium chitosan nanoparticles (TMC NPs)/chitosan (CS)composite sponge with asymmetric wettability surfaces was successfully prepared. The optimum concentrations of TMC NPs and CS were 0.2 mg/mL and 2.0%, respectively. The incorporated TMC NPs could improve the antibacterial activity of the CS sponge. Asymmetric modification enables the CS sponge to have hydrophobic outer surface and hydrophilic inner surface. The hydrophobic surface of the sponge shows waterproof and anti-adhesion contaminant properties, whereas the hydrophilic surface preserves water-absorbing capability and efficiently inhibits the growth of bacteria. More importantly, in vivo chronic wound healing model evaluation reveals that TMC NPs/CS composite sponge promotes the wound healing and accelerates re-epithelialization and angiogenesis. And in vivo anti-infection test shows the TMC NPs/CS composite sponge could effectively prevent wound infection. These findings demonstrate that TMC NPs/CS composite sponge is a promising dressing material for chronic wounds.


Assuntos
Antibacterianos/administração & dosagem , Bandagens , Quitosana/administração & dosagem , Nanopartículas/administração & dosagem , Compostos de Amônio Quaternário/administração & dosagem , Cicatrização/efeitos dos fármacos , Animais , Antibacterianos/química , Linhagem Celular , Sobrevivência Celular/efeitos dos fármacos , Quitosana/química , Diabetes Mellitus Experimental/tratamento farmacológico , Sistemas de Liberação de Medicamentos , Escherichia coli/efeitos dos fármacos , Escherichia coli/crescimento & desenvolvimento , Masculino , Camundongos , Nanopartículas/química , Compostos de Amônio Quaternário/química , Staphylococcus aureus/efeitos dos fármacos , Staphylococcus aureus/crescimento & desenvolvimento
5.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi ; 33(12): 1547-1551, 2019 Dec 15.
Artigo em Chinês | MEDLINE | ID: mdl-31823556

RESUMO

Objective: To investigate the effectiveness of local injection of autologous platelet-rich plasma (PRP) in treatment of diabetic foot ulcer. Methods: Between October 2017 and October 2018, 90 diabetic foot ulcer patients who met the selection criteria were randomly divided into 3 groups: PRP injection group (group A, PRP was injected and hydrogel dressing covered the wounds), PRP covered group (group B, PRP gel and hydrogel dressing covered the wounds), and the control group (group C, hydrogel dressing covered the wounds), 30 cases in each group. There was no significant difference in gender, age, injured side, disease duration, preoperative glycosylated hemoglobin, wound size, and Wagner grading between groups (P>0.05). The frequency of treatments and hospitalization day in all groups and the total amount of PRP application in groups A and B were recorded. The wound healing condition was recorded during the treatment, and the wound healing rate was calculated at 3 months after the first debridement. Results: The frequency of treatments in groups A, B, and C were (10.2±0.8), (11.4±0.6), (12.5±0.5) times, respectively. The total amount of PRP application of groups A and B were (306±24) and (342±18) mL, respectively. There was no significant difference in the frequency of treatments and the total amount of PRP application between groups (P>0.05). The hospitalization days of groups A, B, and C were (40.5±1.8), (62.1±2.3), and (88.6±1.4) days, respectively, showing significant differences between groups (P<0.05). In the course of treatment, the necrosis and exudation of the wounds gradually reduced, the areas of wounds gradually reduced; and the above conditions of group A were significantly better than groups B and C, and group B was better than group C. At 3 months after the first debridement, the wound healing rates of groups A, B, and C were 93.2%±0.8%, 52.1%±1.1%, and 21.3%±1.3%, respectively, with significant differences between groups (P<0.05). Conclusion: PRP can effectively promote the repair of diabetic foot ulcer. The effectiveness of local injection of PRP is superior to the local coverage.


Assuntos
Pé Diabético , Plasma Rico em Plaquetas , Bandagens , Pé Diabético/terapia , Humanos , Injeções , Cicatrização
6.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi ; 36(6): 1055-1059, 2019 Dec 25.
Artigo em Chinês | MEDLINE | ID: mdl-31875383

RESUMO

As a temporary skin substitute, the dressings can protect the wound, stop bleeding, prevent infection and contribute to wound healing. According to the characteristics of the materials, wound dressings can be classified into traditional wound dressings, interactive dressings, bioactive dressings, tissue engineering dressings and smart dressings, etc. Different dressings have different characteristics, and some products have been widely used in clinic. Recently nanomaterials and three-dimensional bio-printing technology have significantly improved the performance of wound dressings. Future dressings will be developed from single function to multi-function composite, and integrated into an intelligent one. This paper reviews the current research progress and future development prospects of wound dressings.


Assuntos
Bandagens , Cicatrização , Pele Artificial , Engenharia Tecidual
7.
Rev Infirm ; 68(256): 25-27, 2019 Dec.
Artigo em Francês | MEDLINE | ID: mdl-31870474

RESUMO

At the patient's bedside 24 hours a day, the nurse is at the heart of the rehabilitation management of the severely burnt patient: installation, technical dressings, supervision of postures and placement of compressors, to limit the functional consequences to the type of retractable and hypertrophic scars. The nurse takes care of the patient in this long journey leading to social reintegration; from accompaniment to autonomy and acceptance of self-image.


Assuntos
Queimaduras , Bandagens , Queimaduras/psicologia , Queimaduras/reabilitação , Queimaduras/terapia , Humanos , Autoimagem
8.
Rev Infirm ; 68(256): 30-31, 2019 Dec.
Artigo em Francês | MEDLINE | ID: mdl-31870476

RESUMO

Dressings are a real challenge in the care of patients with thermal burns. They help to heal and prevent or treat possible skin infections. Paramedical teams must have a perfect strategy for organizing, managing pain and optimizing hygiene and asepsis rules. The purpose is to facilitate the understanding and implementation of this treatment by suggesting protocols that can be applied by all. It remains essential to mobilize specialized services to promote the evolution of burns.


Assuntos
Bandagens , Queimaduras , Adulto , Queimaduras/complicações , Queimaduras/terapia , Dermatite/etiologia , Humanos , Dor , Cicatrização
9.
J Med Life ; 12(3): 276-283, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31666831

RESUMO

Wound dehiscence is a significant problem faced by surgeons after major abdominal surgery. In this study, it was aimed to select the best incision management system to keep the incision edges together and prevent wound opening, and infection by protecting the incision. In this study, 60 patients who underwent abdominal surgery were evaluated regarding their risk of wound dehiscence. In our clinic, high-risk cases of abdominal surgery are performed, the risk factors being ischemia along the incision line, dirty and contaminated wound, obesity, tension on the suture line, traumatization of the wound site, age at onset (> 65), body mass index (BMI) > 30, diabetes mellitus, chronic obstructive pulmonary disease (COPD), immunosuppressive drug users. A prospective study protocol was planned after ASA (American Society of Anesthesiologists) physical status class assignment. Patients were divided into three groups: patients who underwent a postoperative negative-pressure therapy dressing, patients who underwent subcutaneous aspiration drainage, and patients who received standard dressing. The aim of this study was to evaluate the decompensation, surgical site infection, seroma, hospital stay and costs and to evaluate the results in the postoperative period. Sixty patients were randomized (n = 20, for each group). Thirty-one (51%) of the patients were male, and the mean age was 64.3 ± 8.9 (46-85). The mean BMI was 30.45 ± 7.2. There was no statistically significant difference (p≥0.05) between groups in terms of sex, age, and BMI. The ASA score and surgical interventions were similar between the groups. Wound dehiscence rate was 25% (n = 8), 20% (n = 6) and 3% (n = 1) for the Standard Dressing (SD), Aspiration Drainage (AD) and Negative-Pressure (NP) groups, respectively (p <0.017). Duration of hospitalization was 16.45 ± 6.6, 14.3 ± 7.4 and 8.95 ± 2.8 days (p <0.001) for SD, AD and NP groups, respectively. No statistically significant difference was found between the groups regarding other variables (p≥0.05 for all variables). Negative-pressure wound treatment is an easy, fast and practical technique which reduces lateral tension and swelling. It provides perfusion support and helps to protect the surgical field against external sources of infection.


Assuntos
Tratamento de Ferimentos com Pressão Negativa , Deiscência da Ferida Operatória/terapia , Idoso , Bandagens , Índice de Massa Corporal , Proteína C-Reativa/metabolismo , Feminino , Humanos , Tempo de Internação , Contagem de Leucócitos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Fatores de Risco , Deiscência da Ferida Operatória/sangue , Deiscência da Ferida Operatória/complicações , Deiscência da Ferida Operatória/diagnóstico
10.
Medicine (Baltimore) ; 98(44): e17786, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31689851

RESUMO

RATIONALE: Grade 4 diabetic foot (DF) is a severe infection that causes bone destruction, osteomyelitis, and osteoarticular damage, which, in turn, can lead to serious dry or wet gangrene, or amputation. DF is extremely difficult to treat. PATIENT CONCERNS: A 71-year-old female patient with long-term diabetes complicated with uremia, who undergoes regular hemodialysis 2 to 3 times per week, was admitted with grade 4 DF with Pseudomonas aeruginosa infection, and concomitant vascular occlusion of the lower extremities. The patient had a concurrent nutrition and electrolyte disorder. DIAGNOSES: The patient was diagnosed with type 2 diabetes, grade 4 DF, postamputation of the 2nd toe, vascular occlusion of the lower extremities, atherosclerosis, uremia, hypoproteinemia, and electrolyte disturbances. INTERVENTIONS: Treatment with antibiotics and comprehensive measures aimed at improving nutrition and microcirculation, controlling blood glucose, as well as balancing electrolytes were performed to ameliorate the general conditions. Nibbled debridement was used to remove devitalized tissues each time to maintain as much vital cells as possible. Open therapy was used for necrotic tissues, and dressings therapy was used simultaneously for the infected lesion. This combined treatment, involving open therapy with dressing, is referred to as "semiclosure wound therapy." Negative pressure wound therapy (NPWT) was used after a fistula formed. OUTCOMES: During the treatment procedure, the gangrene 3rd toe was spontaneously shed; the necrotic 1st toe was removed by surgery. The wound gradually healed after 3 months of open therapy combined with dressing. High location amputation was avoided. LESSONS: Semiclosure, which constitutes open therapy combined with the use of dressings, plus NPWT can preserve vital skin cells in the wound and control the aggravation of the infection. It is an effective and novel measure that prevents DF amputation in old patient and promotes wound union.


Assuntos
Desbridamento/métodos , Diabetes Mellitus Tipo 2/complicações , Pé Diabético/terapia , Tratamento de Ferimentos com Pressão Negativa/métodos , Doenças Vasculares Periféricas/terapia , Infecções por Pseudomonas/terapia , Pseudomonas aeruginosa , Idoso , Antibacterianos/uso terapêutico , Bandagens , Terapia Combinada , Diabetes Mellitus Tipo 2/microbiologia , Feminino , Humanos , Doenças Vasculares Periféricas/microbiologia , Infecções por Pseudomonas/microbiologia
11.
Vestn Oftalmol ; 135(5. Vyp. 2): 171-176, 2019.
Artigo em Russo | MEDLINE | ID: mdl-31691656

RESUMO

INTRODUCTION: According to various sources, occurrence rate of keratectasia (KE) after Laser in situ Keratomileusis (LASIK) ranges from 0.04 to 0.2%. No known technique for keratorefractive surgery eliminates the probability. Neither corneal cross-linking, nor implantation of polymeric segments can completely prevent its development. PURPOSE: To treat KE after LASIK with bandage lamellar-optical keratoplasty (BLOK) surgery and to evaluate the results. MATERIAL AND METHODS: The study included 22 patients with KE after LASIK divided into two groups. The first group consisted of 6 patients; they underwent BLOK surgery using a segment transplant 1.5 mm in width and 180-220 µm in thickness. The second group included 16 patients who underwent BLOK surgery using 2.75 mm wide, 290-350 µm thick allogeneic transplant of individual length. The follow-up lasted 4 years. RESULTS: In the first group, uncorrected visual acuity (UCVA) improved by 0.4±007, in the second group - by 0.46±0.15. After two years, two patients had their transplant exchanged for a wider one due to ectasia progression. Corneal refraction was stable at 45.36±1.47 Diopters in all other patients of the first group. In the second group, it was consistently between 40.6 and 45.7 Diopters. The main complication of the BLOK surgery was displacement of the edge of the corneal flap formed during LASIK - occurred in 4 patients. CONCLUSION: Bandage lamellar-optical keratoplasty proved effective in treating patients with KE after LASIK, leading to improvement of visual acuity, strengthening of the cornea and normalization of its surface; it slows further progression of ectasia.


Assuntos
Doenças da Córnea , Transplante de Córnea , Ceratomileuse Assistida por Excimer Laser In Situ , Bandagens , Córnea , Topografia da Córnea , Dilatação Patológica , Humanos , Lasers de Excimer , Complicações Pós-Operatórias
13.
Zhonghua Shao Shang Za Zhi ; 35(9): 690-691, 2019 Sep 20.
Artigo em Chinês | MEDLINE | ID: mdl-31594188

RESUMO

A 67-year-old female patient with incontinent dermatitis complicated with sacrococcygeal pressure ulcer was admitted to our unit in November 2017. The wound was treated with a new dressing based on the concept of wet healing, management of exudation, prevention of infection to promote wound healing. Meanwhile, the fecal incontinence was properly treated with colostomy bag combined with disposable negative pressure drainage device to avoid fecal contamination and aggravation of pressure ulcer. Incontinent dermatitis was treated with wound protective powder and wound protective film. After 14 days of treatment, the wound of pressure ulcer was reduced and the incontinent dermatitis was cured.


Assuntos
Dermatite/enfermagem , Incontinência Fecal/enfermagem , Lesão por Pressão/enfermagem , Idoso , Bandagens , Dermatite/complicações , Feminino , Humanos , Lesão por Pressão/complicações
14.
Niger J Clin Pract ; 22(10): 1328-1334, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31607720

RESUMO

Objective: The aim of the this study was to evaluate the effect of honey on the healing of tooth extraction wounds in children 4‒9 years of age. Subjects and Methods: In the present randomized clinical trial, 51 patients, 4‒9 years of age were selected randomly. All the subjects required extraction of one deciduous molar tooth. The subjects were randomly assigned to two groups. In group 1, after extraction of the tooth, the dentist used a cotton swab applicator to place a layer of honey on a piece of gauze moistened with normal saline solution (NSS) and placed it on the socket. In group 2, honey was not used; rather, NSS was applied. On days 3 and 7 after tooth extraction, the wound sizes were measured. Results: In both groups, the wound sizes decreased significantly on the third day compared with baseline and on the seventh day compared with the third day (P < 0.05). On the third and seventh days after tooth extraction, wound sizes in the honey group were significantly lower than those in the NSS group (P < 0.05). Conclusion: Honey resulted in a decrease in wound sizes and faster healing after extraction of teeth in children. Therefore, use of honey can be recommended after minor surgeries in the oral cavity.


Assuntos
Apiterapia/métodos , Mel , Extração Dentária , Alvéolo Dental , Cicatrização/efeitos dos fármacos , Administração Tópica , Bandagens , Criança , Pré-Escolar , Assistência Odontológica , Feminino , Humanos , Masculino , Cloreto de Sódio/uso terapêutico , Alvéolo Dental/efeitos dos fármacos , Alvéolo Dental/patologia , Resultado do Tratamento
15.
Prensa méd. argent ; 105(9 especial): 521-525, oct 2019. tab
Artigo em Inglês | LILACS, BINACIS | ID: biblio-1046371

RESUMO

Over the last decade, the interest in using bacterial cellulose in medicine has increased. The article publishes the data about the efficiency of healing burn wounds in rabbits in experimental conditions with the use of the DermaRM wound dressing, compared to the traditionally used Panthenol ointment and the Branolind N salve dressing


Assuntos
Animais , Coelhos , Pomadas/uso terapêutico , Bandagens , Queimaduras/terapia , Celulose/uso terapêutico , Resultado do Tratamento , Tempo para o Tratamento
17.
J Photochem Photobiol B ; 199: 111593, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31505420

RESUMO

Greener way of synthesizing nanoparticles has emerged as a substitute method, as it is ecological and cost effectual. Numerous efforts have been completed for green synthesis of silver oxide nanoparticles (Ag2O NPs) by various plant extracts. Current work disclosed the green combustion synthesis of Ag2O NPs by using Lippia citriodora plant powder. Furthermore, photocatalytic properties of Ag2O NPs were studied on acid orange 8(AO8) dye was assessed under UV light irradiation. The catalyst shows good photocatalytic activity (PCA) for the degradation of AO8 dye, NPs synthesized by Lippia citriodora powder shows high percentage of degradation. The Ag2O NPs act as excellent antibacterial against S. Aureus and antifungal activity against A. Aureus. Further wound healing studies in excision skin wound model in albino wistar rats showed the effective wound healing activity of Ag2O NPs incorporated hydrogels compared to untreated and plant extract treatments. The majority upshot of this research will be recommended that biologically synthesized Ag2O from Lippia citriodora plant powder has more valuable against various disease-causing pathogens and hence could be useful for developing wound dressing agents for nursing care.


Assuntos
Anti-Infecciosos/química , Lippia/química , Nanopartículas Metálicas/química , Óxidos/química , Extratos Vegetais/química , Compostos de Prata/química , Cicatrização/efeitos dos fármacos , Animais , Anti-Infecciosos/farmacologia , Compostos Azo/química , Bandagens , Benzenossulfonatos/química , Catálise , Estabilidade de Medicamentos , Química Verde , Hidrogéis/química , Masculino , Metilcelulose/química , Testes de Sensibilidade Microbiana , Oxirredução , Óxidos/farmacologia , Processos Fotoquímicos , Ratos Wistar , Compostos de Prata/farmacologia , Staphylococcus aureus/efeitos dos fármacos , Propriedades de Superfície , Resultado do Tratamento
18.
J Wound Care ; 28(9): 639-640, 2019 09 02.
Artigo em Inglês | MEDLINE | ID: mdl-31513495

Assuntos
Bandagens , Biofilmes
19.
J Wound Care ; 28(9): 640-641, 2019 09 02.
Artigo em Inglês | MEDLINE | ID: mdl-31513502

Assuntos
Bandagens
20.
Int J Oral Maxillofac Implants ; 34(5): 1202-1212, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31528865

RESUMO

PURPOSE: Ridge preservation limits dimensional changes after tooth extraction. However, it is still unclear if using a membrane may be advantageous over a collagen wound dressing. Therefore, the goal of this report was to evaluate the outcomes of ridge preservation using freeze-dried bone allograft with a collagen wound dressing. MATERIALS AND METHODS: This study included 21 patients who had one molar extracted, and the site received ridge preservation using freeze-dried bone allograft and a collagen wound dressing (test 2 group). Patients had two standardized cone beam computed tomography (CBCT) scans, taken within 72 hours and 3 months after extraction, to measure changes in ridge height and width, and buccal and lingual plate thicknesses. Changes in keratinized tissue width were recorded. Three-arm analyses were performed using historic data from a previous randomized controlled trial by the same study group, in which 20 molar sites received a collagen wound dressing alone (control) and 20 received ridge preservation with freeze-dried bone allograft and a dense polytetrafluoroethylene membrane (test 1) using the same methodology. RESULTS: There was a statistically significant difference in mean buccal ridge height changes between the control group (2.6 ± 2.06 mm) and test 2 group (1.55 ± 0.93 mm) but no difference in ridge and keratinized tissue width changes between groups. No correlation was found between buccal plate thickness and ridge width change. CONCLUSION: Freeze-dried bone allograft with collagen wound dressing as a barrier was used successfully for ridge preservation in intact molar extraction sites (< 50% bone loss) and can be considered as a treatment alternative to freeze-dried bone allograft with a dense polytetrafluoroethylene membrane.


Assuntos
Perda do Osso Alveolar , Aumento do Rebordo Alveolar , Transplante Ósseo , Aloenxertos , Processo Alveolar , Bandagens , Colágeno , Humanos , Dente Molar , Extração Dentária , Alvéolo Dental
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