Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 3.242
J Clin Nurs ; 29(15-16): 2820-2833, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32279369


AIMS AND OBJECTIVES: To review the literature related to the outcomes and experience of people receiving nurse-led care for chronic wounds in the community. BACKGROUND: Chronic wounds lead to a poor quality of life and are an economic burden to the Australian healthcare system. A lack of awareness into the significance of chronic wounds leads to limited resources being available to facilitate the provision of evidence-based care. The majority of chronic wounds are managed by nurses in the community, and a better understanding into current models of care is required to inform future practice. DESIGN: A systematic quantitative literature review. METHODS: A systematic search was conducted in four electronic databases, and the inclusion criteria were as follows: English language, peer-reviewed, published from 2009-2019 and primary research. The data were compiled into an Excel database for reporting as per the Pickering and Byrne (Higher Education Research & Development, 33, 534.) method of systematic quantitative literature review. This review used the PRISMA checklist. The Mixed Methods Appraisal Tool was used for quality appraisal. RESULTS: Twelve studies were included in the review. Home nursing care, social community care and nursing within a wound clinic were identified as three types of nurse-led care in the literature. The findings demonstrate that nurse-led care was cost-effective, reported high levels of client satisfaction and contributed to improved wound healing and reduced levels of pain. CONCLUSIONS: Nurse-led care is a positive experience for people with chronic wounds and leads to better outcomes. The findings suggested a need for further client education and specialised training for healthcare practitioners managing chronic wounds. RELEVANCE TO CLINICAL PRACTICE: This review demonstrates that nurse-led care for people with chronic wounds in the community is cost-effective and improves client outcomes. Raising awareness into the significance of chronic wounds aims to promote the resources required to facilitate evidence-based care.

Enfermagem em Saúde Comunitária/normas , Padrões de Prática em Enfermagem/normas , Ferimentos e Lesões/enfermagem , Austrália , Doença Crônica/enfermagem , Humanos , Enfermeiras Clínicas/organização & administração , Avaliação de Processos e Resultados em Cuidados de Saúde , Satisfação do Paciente , Padrões de Prática em Enfermagem/economia , Qualidade de Vida , Cicatrização
Br J Nurs ; 29(5): S28-S35, 2020 Mar 12.
Artigo em Inglês | MEDLINE | ID: mdl-32167812


BACKGROUND: Surgical and wound site infections (SWSIs) are the second most frequent type of healthcare-associated Infection. One way of preventing SWSIs is by adhering to the principles of asepsis. However, many nurses struggle to apply the principles of aseptic non-touch technique (ANTT) during wound management. AIM: To identify the barriers and enablers that influence nurses' adherence to the principles of ANTT during wound care. METHOD: A literature search using a systematic approach was carried out. Four databases were searched to identify relevant studies published between January 1993 and December 2018. Titles and abstracts were reviewed. Studies that met the inclusion criteria were reviewed for quality. The extracted data were then synthesised. FINDINGS: A total of seven studies fulfilled the requirements for inclusion. Three themes emerged and were found to be the most dominant factors influencing adherence to the principles of ANTT: material and resources, nurse education, and nurses' behaviour. CONCLUSION: Nurses' compliance with aseptic practice is directly influenced by environmental and psychological factors. Ensuring compliance to ANTT may require an integrated approach involving local, national and worldwide organisations, in collaboration with higher education institutions that teach nurses and similar healthcare professionals.

Infecção Hospitalar/prevenção & controle , Cicatrização , Ferimentos e Lesões/enfermagem , Ferimentos e Lesões/terapia , Humanos
J Trauma Nurs ; 27(1): 29-36, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31895316


Traumatic injury survivors often face a difficult recovery. Surgical and invasive procedures, prolonged monitoring in the intensive care unit (ICU), and constant preventive vigilance by medical staff guide standards of care to promote positive outcomes. Recently, patients with traumatic injuries have benefited from early mobilization, a multidisciplinary approach to increasing participation in upright activity and walking. The purpose of this project was to determine the impact of an early mobility program in the trauma ICU on length of stay (LOS), ventilator days, cost, functional milestones, and rehabilitation utilization. A quality improvement project compared outcomes and cost before and after the implementation of an early mobility program. The trauma team assigned daily mobility levels to trauma ICU patients. Nursing and rehabilitation staff collaborated to set daily goals and provide mobility-based interventions. Forty-four patients were included in the preintervention group and 43 patients in the early mobility group. Physical therapy and occupational therapy were initiated earlier in the early mobilization group (p = .044 and p = .026, respectively). Improvements in LOS, duration of mechanical ventilation, time to out-of-bed activity and walking, and discharge disposition were not significant. There were no adverse events related to the early mobility initiative. Activity intolerance resulted in termination of 7.1% of mobility sessions. The development and initiation of a trauma-specific early mobility program proved to be safe and reduce patient care costs. In addition, the program facilitated earlier initiation of physician and occupational therapies. Although not statistically significant, retrospective data abstraction provides evidence of fewer ICU and total hospital days, earlier extubations, and greater proactive participation in functional activities.

Deambulação Precoce/economia , Deambulação Precoce/enfermagem , Unidades de Terapia Intensiva/economia , Melhoria de Qualidade/economia , Centros de Traumatologia/economia , Ferimentos e Lesões/economia , Ferimentos e Lesões/enfermagem , Adulto , Idoso , Currículo , Deambulação Precoce/estatística & dados numéricos , Educação Médica Continuada/organização & administração , Feminino , Humanos , Unidades de Terapia Intensiva/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Melhoria de Qualidade/estatística & dados numéricos , Centros de Traumatologia/estatística & dados numéricos
J Trauma Nurs ; 27(1): 50-57, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31895320


Trauma nurses are exposed to suffering, death and dying, and vicarious trauma, which may result in nurses experiencing posttraumatic stress disorder (PTSD). This study aims to investigate the extent of PTSD and the effect of the frequency of traumatic events, coping strategies, and social support on PTSD in South Korean trauma nurses. A cross-sectional study was conducted. Participants were 145 trauma nurses recruited from 6 regional trauma centers in Korea. The data were collected through convenience sampling using self-administered questionnaires, including the Korean version of Impact of Event Scale-Revised (IES-R-K), the frequency of traumatic events, coping strategies, and social support. The data were analyzed with descriptive statistics, t test, analysis of variance, Pearson's correlation coefficients, and multiple linear regression. The prevalence of IES-R-K score of 25 or more (indicating a high risk of PTSD) was detected in 57.2% of the trauma nurses. The frequency of traumatic events, work at traumatic emergency units, dysfunctional coping, emotion-focused coping, and social support were found to be significantly associated with PTSD. Therefore, it is necessary to develop PTSD management programs in order to provide effective coping strategies and social support for relieving PTSD symptoms. At the same time, efforts to improve the working environment are needed.

Adaptação Psicológica , Recursos Humanos de Enfermagem no Hospital/psicologia , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Transtornos de Estresse Pós-Traumáticos/etiologia , Estresse Psicológico , Ferimentos e Lesões/enfermagem , Adulto , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , República da Coreia/epidemiologia , Inquéritos e Questionários
J Nurs Care Qual ; 35(1): 63-69, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-30973427


BACKGROUND: Access to both valid and reliable nursing-sensitive indicators is currently limited in primary care. PURPOSE: The objectives were to (1) measure primary care nursing indicators using a wound care tracer condition and (2) study the associations between process and outcome indicators. METHODS: We conducted a longitudinal study in an ambulatory care clinic in Quebec, Canada. The sample included 482 episodes of care. We studied 5 indicators related to processes and 3 to outcomes. RESULTS: Performance levels were moderately high for indicators of initial assessment and duration and low for those of continuity and education. Associations between nursing follow-up and continuity indicators and 3 outcome indicators were highly significant. CONCLUSION: Continuity and nursing follow-up are associated with improved outcomes. Increasing these indicators' performance level can improve both nursing processes and patient outcomes.

Enfermagem de Atenção Primária/normas , Indicadores de Qualidade em Assistência à Saúde/classificação , Ferimentos e Lesões/enfermagem , Adulto , Idoso , Instituições de Assistência Ambulatorial/organização & administração , Instituições de Assistência Ambulatorial/estatística & dados numéricos , Feminino , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Enfermagem de Atenção Primária/métodos , Enfermagem de Atenção Primária/estatística & dados numéricos , Indicadores de Qualidade em Assistência à Saúde/estatística & dados numéricos , Quebeque , Cicatrização/efeitos dos fármacos , Cicatrização/fisiologia , Ferimentos e Lesões/epidemiologia
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 12: 730-736, jan.-dez. 2020. ilus
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem | ID: biblio-1099476


The study's purpose has been to map scientific evidence on interventions targeting people with wounds in palliative care. Methods: It is a scoping review conducted with studies in Portuguese, English, and Spanish, from national and international databases, published from 2010 to 2019. Results: 41 publications from 14 nationalities were included. Studies have as their main theme the evaluation and treatment of wounds of different etiologies. The interventions were presented concerning aspects of care management, basic stages of wound care, psychosocial, and spiritual aspects. Conclusion: Careful assessment of the patient and wound is required. If the parameters are favorable to healing, the team will adopt specific therapy to achieve it. Otherwise, care should include more conservative and less invasive techniques, management of signs and symptoms, and interventions aimed at the social, psychological, and spiritual impacts related to the wound

Objetivo: Mapear evidências científicas sobre intervenções direcionadas a pessoas com feridas em cuidados paliativos. Método: Revisão de Escopo realizada com estudos em português, inglês e espanhol, provenientes de bases de dados nacionais e internacionais, publicados no período de 2010 a 2019. Resultados: Foram incluídas 41 publicações oriundas de 14 nacionalidades. Os estudos apresentam como principal temática a avaliação e tratamento de feridas de diferentes etiologias. As intervenções foram apresentadas em relação aos aspectos da gestão do cuidado, etapas básicas do cuidado da ferida, aspectos psicossociais e espirituais. Conclusão: É necessária uma avaliação criteriosa do paciente e da ferida. Caso os parâmetros sejam favoráveis à cicatrização, a equipe adotará a terapêutica específica para alcançá-la. Caso contrário, o cuidado deverá incluir realização de técnicas mais conservadoras e menos invasivas, manejo de sinais e sintomas, além de intervenções voltadas aos impactos sociais, psicológicos e espirituais relacionados à ferida

Objetivo: El propósito del trabajo es mapear evidencia científica sobre intervenciones dirigidas a personas con heridas en cuidados paliativos. Método: Revisión del alcance realizada con estudios en portugués, inglés y español, de bases de datos nacionales e internacionales, publicados de 2010 a 2019. Resultados: Se incluyeron 41 publicaciones de 14 nacionalidades. Los estudios tienen como tema principal la evaluación y el tratamiento de heridas de diferentes etiologías. Las intervenciones se presentaron en relación con aspectos de la gestión asistencial, etapas básicas del cuidado de heridas, aspectos psicosociales y espirituales. Conclusión: Se requiere una cuidadosa evaluación del paciente y la herida. Si los parámetros son favorables para la curación, el equipo adoptará una terapia específica para lograrlo. De lo contrario, la atención debe incluir técnicas más conservadoras y menos invasivas, manejo de signos y síntomas e intervenciones dirigidas a los impactos sociales, psicológicos y espirituales relacionados con la herida

Humanos , Masculino , Feminino , Cuidados Paliativos/métodos , Ferimentos e Lesões/enfermagem , Cuidados de Enfermagem , Ferimentos e Lesões/terapia
Br J Community Nurs ; 24(Sup12): S22-S25, 2019 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-31804886


Community nurses regularly treat patients with chronic wounds (those persisting over 6 weeks); with the complexity of both the patients' health needs and the wound itself, this often becomes a highly time-consuming task for the nurse. Wound assessment tools are designed to support all qualified nurses, regardless of whether the nurse possesses specialist wound care knowledge or not, in delivering safe and appropriate wound care. The wound assessment tool, using the acronym TIME, has been recently amended to now be known as TIMERS (Tissue, Infection/Inflammation, Moisture, Wound edge, Repair/Regeneration, Social). This article will examine what the newly amended wound assessment tool TIMERS represents, in addition to looking at the practical issues around its implementation in community settings.

Enfermagem em Saúde Comunitária , Higiene da Pele/enfermagem , Ferimentos e Lesões/enfermagem , Doença Crônica , Enfermagem Holística , Humanos , Úlcera Cutânea/enfermagem
Rev. bras. enferm ; 72(6): 1562-1570, Nov.-Dec. 2019. tab
Artigo em Inglês | LILACS, BDENF - Enfermagem | ID: biblio-1042164


ABSTRACT Objective: to present evidence of validity of an instrument aimed at evaluating the knowledge of nursing students about the care of the wounded patient, according to the difficulty and discrimination indexes of the items. Method: methodological study conducted in a nursing higher education institution with 117 undergraduate students and 38 professionals from a research group with experience in the area of wounds. For data collection, a questionnaire with 10 multiple choice questions was applied before and after classes on wounds. Results: most of the questions presented low level of difficulty and inefficient discrimination index, requiring a revision of the instrument. After two review stages, the difficulty and discrimination indexes of the instruments improved. Conclusion: an instrument with better evidence of validity was obtained. However, it still requires refinement for later revalidation in the same population.

RESUMEN Objetivo: identificar las evidencias de validez según los índices de dificultad y discriminación de los ítems de un instrumento con el fin de evaluar el conocimiento de académicos de enfermería en el cuidado de la persona lesionada. Método: se trata de un estudio metodológico desarrollado en una institución de enseñanza superior de enfermería realizado entre 117 estudiantes de graduación y 38 profesionales con experiencia en el área de heridas pertenecientes a un grupo de investigación. Se recogieron los datos mediante un cuestionario de 10 preguntas de opción múltiple, aplicado antes y después de las clases sobre heridas. Resultados: la mayoría de las cuestiones presentó un nivel bajo de dificultad y poder discriminativo ineficiente, haciéndose necesaria la revisión del instrumento. Tras dos etapas de revisión, el cuestionario demostró una mejoría de los índices de dificultad y discriminación. Conclusión: se logró un instrumento con mejor evidencia de validez, aunque tuvo que ser perfeccionado para su posterior revalidación en la misma población.

RESUMO Objetivo: Identificar as evidências de validade, segundo os índices de dificuldade e discriminação dos itens, de um instrumento para avaliação do conhecimento de acadêmicos de enfermagem no cuidado à pessoa com lesão. Método: Estudo metodológico desenvolvido em instituição de ensino superior de enfermagem com 117 estudantes de graduação e 38 profissionais componentes de grupo de pesquisa com experiência na área de feridas. Para coleta de dados, utilizou-se um questionário com 10 questões de múltipla escolha, aplicado antes e após as aulas de feridas. Resultados: A maioria das questões apresentou baixo nível de dificuldade e poder discriminativo ineficiente, sendo necessária a revisão do instrumento. Após duas etapas de revisão, o questionário apresentou melhora dos índices de dificuldade e discriminação. Conclusão: Obteve-se um instrumento com melhores evidências de validade, embora com necessidade de refinamento para posterior revalidação na mesma população.

Humanos , Masculino , Feminino , Adolescente , Adulto , Adulto Jovem , Estudantes de Enfermagem , Ferimentos e Lesões/enfermagem , Inquéritos e Questionários , Avaliação Educacional/métodos , Pele/lesões , Reprodutibilidade dos Testes , Competência Clínica , Educação em Enfermagem , Pessoa de Meia-Idade
Rev Bras Enferm ; 72(6): 1562-1570, 2019.
Artigo em Inglês, Português | MEDLINE | ID: mdl-31644745


OBJECTIVE: to present evidence of validity of an instrument aimed at evaluating the knowledge of nursing students about the care of the wounded patient, according to the difficulty and discrimination indexes of the items. METHOD: methodological study conducted in a nursing higher education institution with 117 undergraduate students and 38 professionals from a research group with experience in the area of wounds. For data collection, a questionnaire with 10 multiple choice questions was applied before and after classes on wounds. RESULTS: most of the questions presented low level of difficulty and inefficient discrimination index, requiring a revision of the instrument. After two review stages, the difficulty and discrimination indexes of the instruments improved. CONCLUSION: an instrument with better evidence of validity was obtained. However, it still requires refinement for later revalidation in the same population.

Avaliação Educacional/métodos , Estudantes de Enfermagem , Inquéritos e Questionários , Ferimentos e Lesões/enfermagem , Adolescente , Adulto , Competência Clínica , Educação em Enfermagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Pele/lesões , Adulto Jovem
Rev Gaucha Enferm ; 40: e20180421, 2019.
Artigo em Português, Inglês | MEDLINE | ID: mdl-31576970


OBJECTIVE: Map specific skills of the Wound Navigator. METHODS: A scoping review of complete and free articles in the databases CINAHL®, Nursing & Allied Health Collection, Cochrane Plus Collection, MedicLatina, MEDLINE® and 12 specialist associations in tissue viability, references in Portuguese, English, Spanish and French, with no time limit. Realized by two researchers in August 2017, of the 746 articles found, 19 met the inclusion and exclusion criteria. RESULTS: Four competency domains were identified: care (prevention/treatment of wounds and advanced therapies, decision-making; empowerment and clinical supervision), quality (specialized training; peer qualification; research and audit), and leadership (change agent; teamwork and consultant) and management (material selection/cost control). CONCLUSIONS: With four areas of competences, the Wound Navigator in partnership focuses on redefining people's life plans in the presence of wounds.

Competência Clínica , Enfermeiras Especialistas , Ferimentos e Lesões/enfermagem , Humanos , Papel do Profissional de Enfermagem
Nursing ; 49(10): 32-39, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31568079


The clinical nurse may be the first caregiver to assess changes in a patient's skin and initiate wound care. This article provides practical guidelines that any nurse can implement.

Guias de Prática Clínica como Assunto , Higiene da Pele/enfermagem , Ferimentos e Lesões/enfermagem , Administração Tópica , Humanos , Avaliação em Enfermagem , Ferimentos e Lesões/etiologia
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 11(5): 1219-1225, out.-dez. 2019. tab
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem | ID: biblio-1022336


Objetivo: Avaliar os efeitos da irradiação ultrassônica de baixa frequência no tratamento de úlcera venosa. Método: Estudo de aplicação de tecnologia em saúde, realizado com indivíduos com lesões venosas, no ano de 2017 entre os meses de abril a agosto, utilizado formulário estruturado para coleta, analisados no programa Excel e representados em tabela e estatística descritiva. Resultados: Participaram cinco pacientes, três mulheres entre 65 e 88 anos de idade. Os participantes apresentaram cinco úlceras venosas, maioria localizada na porção inferior da perna. Houve redução mínima de 2,5% e máxima de 35,8% sobre a área das lesões. Um participante apresentou 100,0% de epitelização e os demais apresentaram tecido de granulação maior ou igual a 70,0%. Encontrou-se redução máxima de 10 pontos na PUSH, redução mínima de 2 pontos. Conclusão: A terapia ultrassônica traz aspectos positivos para o processo de reparação tecidual

Objective: The study's purpose has been to assess the effects of low-frequency ultrasound irradiation in the treatment of venous ulcer. Methods: It is a health technology application study, which was performed with individuals bearing venous lesions. The research was carried out over 2017 from April to August, using a structured form for data collection, where such data was analyzed in the Excel program and represented through tables and descriptive statistics. Results: Five patients have participated, being three women within the age group from 65 to 88 years old. The participants had five venous ulcers, predominantly located in the leg's lower portion. There was a reduction in the lesion area ranging from 2.5% (minimum) to 35.8% (maximum). One participant achieved 100% epithelization, and the others showed granulation tissue greater or equal to 70.0%. There was a maximum reduction of 10 points in the Pressure Ulcer Scale for Healing (PUSH), and a minimum reduction of 2 points. Conclusion: The low-frequency ultrasound therapy produces positive aspects to the tissue healing process

Objetivo: Evaluar los efectos de la irradiación ultrasónica de baja frecuencia en el tratamiento de úlcera venosa. Método: Estudio de aplicación de tecnología en salud, realizado con individuos con lesiones venosas, en el año 2017 entre los meses abril a agosto, utilizado formulario estructurado para recolección, analizados en el programa Excel y representados en tabla y estadística descriptiva. Resultados: Participaron cinco pacientes, tres mujeres entre 65 y 88 años de edad. Presentaron cinco úlceras venosas, mayoría localizada en la porción inferior de la pierna. Se observó una reducción mínima del 2,5% y una máxima del 35,8% sobre el área de las lesiones. Un participante presentó 100,0% de epitelización y los demás presentaron tejido de granulación mayor o igual al 70,0%. Se encontró reducción máxima de 10 puntos en la PUSH, reducción mínima de 2 puntos. Conclusión: La terapia ultrasónica trae aspectos positivos para el proceso de reparación del tejido

Humanos , Masculino , Feminino , Idoso , Idoso de 80 Anos ou mais , Terapia por Ultrassom/enfermagem , Úlcera Varicosa/terapia , Cicatrização , Ferimentos e Lesões/enfermagem , Ferimentos e Lesões/terapia , Tecnologia Biomédica/métodos
Br J Community Nurs ; 24(Sup9): S19-S23, 2019 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-31479334


Malignant wounds are a complication of cancer, and usually occur in those individuals with advanced disease. When healing ceases to be the goal, treatment is centred around symptom control and improving quality of life. Caring for individuals with malignant wounds presents challenges for patients, their families and nurses alike. This article discusses the holistic management of malignant wounds, with an emphasis on the control of both physical and psychosocial symptoms of wound management, as well as the impact that this may have on all those involved. Common physical symptoms of malignant wounds include malodour, bleeding, pain, exudate and pruritis. Psychosocial symptoms may result in social isolation and depression. All these symptoms have a huge impact, not only on patients and their families, but also on healthcare professionals both during and after care. Managing these symptoms requires a multidisciplinary approach to facilitate the best possible outcomes for patients and their caregivers.

Saúde Holística , Enfermagem de Cuidados Paliativos na Terminalidade da Vida/métodos , Neoplasias/enfermagem , Manejo da Dor/métodos , Ferimentos e Lesões/enfermagem , Carvão Vegetal , Depressão/psicologia , Exsudatos e Transudatos , Hemorragia/etiologia , Hemorragia/enfermagem , Humanos , Neoplasias/complicações , Odorantes , Dor/enfermagem , Prurido/etiologia , Prurido/enfermagem , Qualidade de Vida , Isolamento Social/psicologia , Ferimentos e Lesões/etiologia , Ferimentos e Lesões/psicologia
Br J Community Nurs ; 24(Sup9): S26-S32, 2019 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-31479336


The immense burden imposed by chronic wounds-those persisting over 6 weeks despite active intervention-on patients and health services is well recognised. There are various reasons for why a wound fails to progress towards closure, and clinicians must investigate the underlying cause of wound chronicity, as this information guides the management of such wounds. The TIME framework (T=tissue; I=infection/inflammation; M=moisture balance; E=wound edges) is a useful tool for practitioners to systematically undertake wound assessment and product selection. This article discusses chronic wound management based on the TIME framework, examining the aspects to be considered when managing chronic wounds. It also describes the process of dressing selection for overcoming the various barriers to wound healing, specifically discussing the AQUACEL family of dressings.

Bandagens , Cicatrização , Infecção dos Ferimentos/enfermagem , Ferimentos e Lesões/enfermagem , Carboximetilcelulose Sódica , Doença Crônica , Humanos , Inflamação , Sobrevivência de Tecidos , Infecção dos Ferimentos/diagnóstico
Br J Community Nurs ; 24(Sup9): S33-S37, 2019 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-31479338


One of the biggest challenges faced by healthcare providers is the treatment of chronic, non-healing wounds. This paper reports for the first time in the UK the results of five case studies in which a novel regenerating matrix-based therapy, CACIPLIQ20, was used. CACIPLIQ20 is a heparan sulphate mimetic designed to replace the destroyed heparan sulphate in the extracellular matrix of wound cells. All five patients in this case series had chronic, non-healing ulcers that had not improved with conventional care. Treatment included two applications of CACIPLIQ20 per week, for a maximum of 12 weeks. Three of the five wounds healed completely, and the remaining two showed significant improvements in size and quality. The treatment was well tolerated by the patients and also led to a significant reduction in pain. Moreover, CACIPLIQ20 treatment was found to be highly cost-effective when compared to conventional care, with the potential to save healthcare systems significant resources. Further studies are needed to build a strong evidence base on the use of this product, but these preliminary findings are certainly promising.

Bandagens , Glucanos/uso terapêutico , Heparitina Sulfato/análogos & derivados , Inflamação , Lesão por Pressão/enfermagem , Ferida Cirúrgica/enfermagem , Úlcera Varicosa/enfermagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Amputação , Doença Crônica , Análise Custo-Benefício , Matriz Extracelular , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Vasculares Periféricas , Regeneração , Ferimentos e Lesões/enfermagem