Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 37
Filtrar
Mais filtros










Intervalo de ano de publicação
3.
An Bras Dermatol ; 92(4): 546-549, 2017 Jul-Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28954109

RESUMO

Liposarcomas correspond to the most common histological subtype of soft tissue sarcomas. They can be subdivided into: well differentiated or atypical lipoma, undifferentiated, myxoid, round, and pleomorphic cells. Atypical lipomas are the most prevalent and usually appear as asymptomatic softened tumors. They are locally aggressive but rarely lead to distant metastases. The diagnosis of this tumor is based on the imaging and histopathologic findings. Treatment consists of excision surgery with complete tumor removal. It has a good prognosis due to the low percentage of distant metastases. We report a rare case of giant atypical lipoma as well as the adopted therapy and evolution.


Assuntos
Lipoma/patologia , Lipossarcoma/patologia , Neoplasias de Tecidos Moles/patologia , Adulto , Biópsia , Nádegas/patologia , Diagnóstico Diferencial , Humanos , Lipoma/diagnóstico , Lipoma/cirurgia , Lipossarcoma/diagnóstico , Lipossarcoma/cirurgia , Masculino , Neoplasias de Tecidos Moles/diagnóstico , Neoplasias de Tecidos Moles/cirurgia
4.
An. bras. dermatol ; 92(4): 546-549, July-Aug. 2017. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-886990

RESUMO

Abstract: Liposarcomas correspond to the most common histological subtype of soft tissue sarcomas. They can be subdivided into: well differentiated or atypical lipoma, undifferentiated, myxoid, round, and pleomorphic cells. Atypical lipomas are the most prevalent and usually appear as asymptomatic softened tumors. They are locally aggressive but rarely lead to distant metastases. The diagnosis of this tumor is based on the imaging and histopathologic findings. Treatment consists of excision surgery with complete tumor removal. It has a good prognosis due to the low percentage of distant metastases. We report a rare case of giant atypical lipoma as well as the adopted therapy and evolution.

5.
An Bras Dermatol ; 92(2): 256-259, 2017 Mar-Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28538892

RESUMO

Although giant congenital melanocytic nevus is a rare lesion, it causes significant deformity and carries a risk of malignant degeneration. Different surgical techniques for the lesion removal are described, including serial resection, resection with skin grafting, and resection and coverage with expanded skin flap (skin expanders). The aim of this study is to report the author's 40 years of experience with cases requiring at least 4 serial excisions to complete the treatment. Serial resection is an effective, safe, and simple technique that requires a lot of patience. Treatment often results in a single linear scar, requires no donor sites, nor large flaps. It is not subject to potencial complications of expanders and avoid aesthetic deformities depending on the location.


Assuntos
Procedimentos Cirúrgicos Dermatológicos/métodos , Nevo Pigmentado/cirurgia , Neoplasias Cutâneas/cirurgia , Retalhos Cirúrgicos/cirurgia , Humanos , Nevo Pigmentado/complicações , Nevo Pigmentado/congênito , Neoplasias Cutâneas/complicações , Neoplasias Cutâneas/congênito , Fatores de Tempo , Dispositivos para Expansão de Tecidos
6.
An. bras. dermatol ; 92(2): 256-259, Mar.-Apr. 2017. graf
Artigo em Inglês | LILACS-Express | ID: biblio-838054

RESUMO

Abstract: Although giant congenital melanocytic nevus is a rare lesion, it causes significant deformity and carries a risk of malignant degeneration. Different surgical techniques for the lesion removal are described, including serial resection, resection with skin grafting, and resection and coverage with expanded skin flap (skin expanders). The aim of this study is to report the author's 40 years of experience with cases requiring at least 4 serial excisions to complete the treatment. Serial resection is an effective, safe, and simple technique that requires a lot of patience. Treatment often results in a single linear scar, requires no donor sites, nor large flaps. It is not subject to potencial complications of expanders and avoid aesthetic deformities depending on the location.

7.
An Bras Dermatol ; 91(5): 649-651, 2016 Sep-Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27828642

RESUMO

Necrolytic acral erythema is a rare skin disease associated with hepatitis C virus infection. We report a case of a 31-year-old woman with hepatitis C virus infection and decreased zinc serum level. Physical examination revealed scaly, lichenified plaques, well-demarcated with an erythematous peripheral rim located on the lower limbs. After blood transfusion and oral zinc supplementation the patient presented an improvement of lesions.


Assuntos
Eritema/etiologia , Hepatite C/complicações , Dermatoses da Perna/etiologia , Adulto , Eritema/tratamento farmacológico , Eritema/patologia , Feminino , Hepatite C/tratamento farmacológico , Hepatite C/patologia , Humanos , Dermatoses da Perna/tratamento farmacológico , Dermatoses da Perna/patologia , Erupções Liquenoides/patologia , Zinco/deficiência , Zinco/uso terapêutico
8.
An. bras. dermatol ; 91(5): 649-651, Sept.-Oct. 2016. graf
Artigo em Inglês | LILACS-Express | ID: biblio-827745

RESUMO

Abstract: Necrolytic acral erythema is a rare skin disease associated with hepatitis C virus infection. We report a case of a 31-year-old woman with hepatitis C virus infection and decreased zinc serum level. Physical examination revealed scaly, lichenified plaques, well-demarcated with an erythematous peripheral rim located on the lower limbs. After blood transfusion and oral zinc supplementation the patient presented an improvement of lesions.

9.
Dermatol Surg ; 42(2): 183-90, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26845538

RESUMO

BACKGROUND: Racial melanonychia striata is a nail plate dyschromia described as a gray coloration of the background in dermatoscopy and hypermelanosis in histology. However, many cases with brown or black coloration of the background in the dermatoscopic examination have been followed. OBJECTIVE: Evaluate racial melanonychia striata dermatoscopical patterns and histological diagnosis in Fitzpatrick skin Types IV, V, or VI population. MATERIALS AND METHODS: 482 Fitzpatrick skin Types IV, V, or VI patients, between 19 and 72 years of age, were clinically evaluated and underwent nail plate dermatoscopic examination. Fifty-eight patients presenting melanonychia striata and dermatoscopic patterns with brown or black coloration of the background were submitted to a nail matrix biopsy. When occurring in more than 1 digit, biopsy was performed in the lesion with the darkest coloration presented in dermatoscopy. RESULTS: All skin Types IV, V, or VI patients who had melanonychia striata, with brown or black coloration of the background in the dermatoscopic examination, revealed histopathological analysis compatible with hypermelanosis. CONCLUSION: Racial melanonychia in skin Types IV, V, or VI patients, resulting from hypermelanosis, may present brown or black coloration of the background in the dermatoscopic examination.


Assuntos
Doenças da Unha/etnologia , Doenças da Unha/patologia , Transtornos da Pigmentação/etnologia , Transtornos da Pigmentação/patologia , Adolescente , Adulto , Idoso , Biópsia , Dermoscopia , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Melanoma/patologia , Pessoa de Meia-Idade , Neoplasias Cutâneas/patologia , Adulto Jovem
10.
An Bras Dermatol ; 90(2): 211-5, 2015 Mar-Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25830991

RESUMO

The study aimed to verify the therapeutic action of isotretinoin in the treatment of sebaceous hyperplasia. During two months, 20 patients with sebaceous hyperplasia took isotretinoin at a dosage of 1mg/kg per day. Their skin lesions were counted and photographed before and after treatment and re-evaluated two years later. The average number of sebaceous hyperplasia lesions before treatment was 24 per patient. At the end of two months of therapy, the number of lesions decreased to 2 per patient. The statistically analyzed data showed a reduction in the number of lesions following isotretinoin use (p < 0.05). Two years after the end of the treatment, the average number of sebaceous hyperplasia lesions was 4 per patient. There were no severe side effects. Thus, the data analysis suggests that isotretinoin is a safe and effective drug for treating the disease under study.


Assuntos
Fármacos Dermatológicos/uso terapêutico , Isotretinoína/uso terapêutico , Doenças das Glândulas Sebáceas/tratamento farmacológico , Glândulas Sebáceas/patologia , Adulto , Feminino , Humanos , Hiperplasia/tratamento farmacológico , Pele/efeitos dos fármacos , Estatísticas não Paramétricas , Fatores de Tempo , Resultado do Tratamento
11.
An. bras. dermatol ; 90(2): 211-215, Mar-Apr/2015. tab, graf
Artigo em Inglês | LILACS | ID: lil-741061

RESUMO

The study aimed to verify the therapeutic action of isotretinoin in the treatment of sebaceous hyperplasia. During two months, 20 patients with sebaceous hyperplasia took isotretinoin at a dosage of 1mg/kg per day. Their skin lesions were counted and photographed before and after treatment and re-evaluated two years later. The average number of sebaceous hyperplasia lesions before treatment was 24 per patient. At the end of two months of therapy, the number of lesions decreased to 2 per patient. The statistically analyzed data showed a reduction in the number of lesions following isotretinoin use (p < 0.05). Two years after the end of the treatment, the average number of sebaceous hyperplasia lesions was 4 per patient. There were no severe side effects. Thus, the data analysis suggests that isotretinoin is a safe and effective drug for treating the disease under study.


Assuntos
Adulto , Feminino , Humanos , Fármacos Dermatológicos/uso terapêutico , Isotretinoína/uso terapêutico , Doenças das Glândulas Sebáceas/tratamento farmacológico , Glândulas Sebáceas/patologia , Hiperplasia/tratamento farmacológico , Estatísticas não Paramétricas , Pele/efeitos dos fármacos , Fatores de Tempo , Resultado do Tratamento
12.
An Bras Dermatol ; 89(4): 666-8, 2014 Jul-Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25054761

RESUMO

Melanoma is a malignant melanocytic neoplasm with high mortality rate, and steadily and universally increasing incidence rates. Polypoid melanoma is considered an exophytic variant of the nodular subtype. The incidence of polypoid melanoma is extremely variable, most likely because of the different criteria used for its characterization. We presented a rare case of polypoid melanoma and superficial spreading melanoma in the same lesion.


Assuntos
Melanoma/patologia , Neoplasias Cutâneas/patologia , Dermoscopia , Humanos , Pessoa de Meia-Idade , Prognóstico
13.
An. bras. dermatol ; 89(4): 666-668, Jul-Aug/2014. graf
Artigo em Inglês | LILACS | ID: lil-715539

RESUMO

Melanoma is a malignant melanocytic neoplasm with high mortality rate, and steadily and universally increasing incidence rates. Polypoid melanoma is considered an exophytic variant of the nodular subtype. The incidence of polypoid melanoma is extremely variable, most likely because of the different criteria used for its characterization. We presented a rare case of polypoid melanoma and superficial spreading melanoma in the same lesion.


Assuntos
Humanos , Pessoa de Meia-Idade , Melanoma/patologia , Neoplasias Cutâneas/patologia , Dermoscopia , Prognóstico
14.
An Bras Dermatol ; 89(1): 157-9, 2014 Jan-Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24626664

RESUMO

We describe a case of plantar interdigital cutaneous melanoma in a 22-year-old woman who reported changes in a pigmented lesion during pregnancy. Diagnosis was late and evolution unfavourable. The purpose of this report is to draw the attention of dermatologists to the need for careful regular examination of melanocytic lesions in pregnant women, not ignoring possible changes as always physiological.


Assuntos
Doenças do Pé/patologia , Melanoma/patologia , Complicações Neoplásicas na Gravidez/patologia , Neoplasias Cutâneas/patologia , Biópsia , Dermoscopia , Evolução Fatal , Feminino , Humanos , Gravidez , Pele/patologia , Dedos do Pé , Adulto Jovem
15.
An. bras. dermatol ; 89(1): 157-159, Jan-Feb/2014. graf
Artigo em Inglês | LILACS | ID: lil-703549

RESUMO

We describe a case of plantar interdigital cutaneous melanoma in a 22-year-old woman who reported changes in a pigmented lesion during pregnancy. Diagnosis was late and evolution unfavourable. The purpose of this report is to draw the attention of dermatologists to the need for careful regular examination of melanocytic lesions in pregnant women, not ignoring possible changes as always physiological.


Assuntos
Feminino , Humanos , Gravidez , Adulto Jovem , Doenças do Pé/patologia , Melanoma/patologia , Complicações Neoplásicas na Gravidez/patologia , Neoplasias Cutâneas/patologia , Biópsia , Dermoscopia , Evolução Fatal , Pele/patologia , Dedos do Pé
16.
Surg. cosmet. dermatol. (Impr.) ; 6(4): 364-367, Out-Dez.2014. ilus
Artigo em Inglês, Português | LILACS-Express | ID: biblio-817

RESUMO

Preocupados em diminuir as complicações cirúrgicas, os autores descrevem técnica inovadora, a "cerquinha" hemostática realizada com pontos cirúrgicos simples interrompidos. Está indicada para lesões de qualquer dimensão, sendo de simples execução e resultando em aumento da segurança do ato cirúrgico.


With an aim at reducing surgical complications, the authors describe an innovative technique - the hemostatic enclosure - performed with simple interrupted surgical stitches. The technique is indicated for lesions of any size, due to its simple implementation and because it results in the increased safety of surgical procedures.

17.
Surg. cosmet. dermatol. (Impr.) ; 4(3): 264-267, Jul.-Set. 2012. ilus
Artigo em Inglês, Português | LILACS-Express | ID: biblio-877539

RESUMO

Os retalhos são muito utilizados na reconstrução cirúrgica da região nasal. Durante o pósoperatório desses pacientes habitualmente observa-se desnível da cicatriz em relação à pele vizinha, gerando insatisfação estética. Tal queixa frequentemente se mantém mesmo com a abrasão preconizada pela literatura entre 30 e 60 dias após o procedimento. Propõese associação de exereses tangenciais com lâmina de barbear (shavings) de toda a área do retalho até o aplainamento em relação à vizinhança, seguida de dermabrasão para refinamento de irregularidades ainda existentes. Os resultados são excelentes, tornando as cicatrizes menos perceptíveis, fato muito satisfatório em se tratando de área tão importante estética e socialmente


Flaps are widely used in the surgical reconstruction of the nasal region. During the post-operative period, an unattractive depressed scar in relation to the nearby skin can be observed. Even after abrasion ­ which the literature recommends 30-60 days after the procedure ­ this complaint often persists. This study proposes tangential excisions with a razor blade (shaving) of the flap's entire area until it is level with the surrounding region, followed by dermabrasion to refine any remaining irregularities. The results are deemed excellent since the scars become less noticeable ­ a very satisfactory outcome due to the aesthetic and social importance of the treated area.

18.
J Am Acad Dermatol ; 65(2): 297-303, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21531039

RESUMO

BACKGROUND: The dermatoscopic examination of the nail plate has been recently introduced for the evaluation of pigmented nail lesions. There is, however, no evidence that this technique improves diagnostic accuracy of in situ melanoma. OBJECTIVE: To establish and validate patterns for intraoperative dermatoscopy of the nail matrix. METHODS: Intraoperative nail matrix dermatoscopy was performed in 100 consecutive bands of longitudinal melanonychia that were excised and submitted to histopathologic examination. RESULTS: We identified 4 dermatoscopic patterns: regular gray pattern (hypermelanosis), regular brown pattern (benign melanocytic hyperplasia), regular brown pattern with globules or blotch (melanocytic nevi), and irregular pattern (melanoma). LIMITATIONS: Nail matrix dermatoscopy is an invasive procedure that can not routinely be performed in all cases of melanonychia. CONCLUSION: The patterns described present high sensitivity and specificity for intraoperative differential diagnosis of pigmented nail lesions.


Assuntos
Dermoscopia/métodos , Cuidados Intraoperatórios/métodos , Doenças da Unha/patologia , Nevo Pigmentado/patologia , Neoplasias Cutâneas/patologia , Adulto , Idoso , Estudos de Coortes , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças da Unha/diagnóstico , Doenças da Unha/cirurgia , Nevo Pigmentado/diagnóstico , Nevo Pigmentado/cirurgia , Reprodutibilidade dos Testes , Medição de Risco , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/cirurgia
19.
Diagn. tratamento ; 16(2)abr. 2011. ilus, tab
Artigo em Português | LILACS-Express | ID: lil-592279

RESUMO

Contexto: A ictiose ligada ao X é uma genodermatose rara, limitada ao sexo masculino, com herança recessiva ligada ao cromossomo X. Provocada pela deficiência da enzima esteroide-sulfatase (arilsulfatase C), gera distúrbio da queratinização que persiste do nascimento à vida adulta. Caracteriza-se pela presença de escamas escuras, firmemente aderidas e generalizadas, embora as regiões centro-facial e palmo-plantares sejam poupadas. Relato de caso: Dois irmãos do sexo masculino, de 16 e 14 anos, que apresentavam xerose cutânea intensa e difusa, presença de escamas ictiósicas hipercrômicas e poligonais, de distribuição generalizada, poupando região centro-facial. Ambos em investigação de síndrome genética devido a retardo do desenvolvimento neuropsicomotor, baixa estatura, dismorfismos faciais, alterações esqueléticas e corneanas. Discussão: O diagnóstico é confirmado por testes genéticos e bioquímicos; e o tratamento, realizado com agentes tópicos, visando hidratação, lubrificação e queratólise. Conclusões: A atuação de outros especialistas e o aconselhamento genético são de suma importância.

20.
An Bras Dermatol ; 86(1): 74-9, 2011 Jan-Feb.
Artigo em Inglês, Português | MEDLINE | ID: mdl-21437525

RESUMO

BACKGROUNDS: Although easily diagnosed, molluscum contagiosum may present as a single lesion or as several small, inflamed lesions of difficult diagnosis. OBJECTIVE: To describe the dermoscopic characteristics of molluscum contagiosum and to compare the findings from clinical examination and dermoscopy. METHODS: Histopathologically confirmed lesions were evaluated clinically and dermoscopically in 57 patients. RESULTS: At clinical examination and dermoscopy of 211 lesions, orifices were visualized in 50.24% and 96.68% of the lesions, and vessels in 6.16% and 89.10%, respectively. The vascular patterns found in the 188 lesions in which vessels were found at dermoscopy were the crown (72.34%), radial (54.25%) and punctiform patterns (20.21%). Half of the 188 lesions had a combination of vascular patterns, with the flower pattern (a new vascular pattern) being found in 19.68% of cases. More orifices and vessels were identified at dermoscopy than at clinical examination, including cases with inflammation or perilesional eczema and small lesions. Punctiform vessels were associated with inflammation, excoriation and perilesional eczema. CONCLUSIONS: Dermoscopy performed on molluscum contagiosum lesions proved superior to dermatological examination even in cases in which clinical diagnosis was difficult. The presence of orifices, vessels and specific vascular patterns aids diagnosis, including differential diagnosis with other types of skin lesion.


Assuntos
Dermoscopia/métodos , Molusco Contagioso/patologia , Adolescente , Adulto , Vasos Sanguíneos/patologia , Distribuição de Qui-Quadrado , Criança , Pré-Escolar , Diagnóstico Diferencial , Feminino , Humanos , Lactente , Masculino , Pele/patologia , Adulto Jovem
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA