Detalhe da pesquisa
1.
Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus.
Eukaryot Cell
; 14(9): 941-57, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26150413
2.
Bioisosteric approach to the discovery of imidazo[1,2-a]pyrazines as potent Aurora kinase inhibitors.
Bioorg Med Chem Lett
; 21(1): 592-8, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21075632
3.
Discovery of orally bioavailable imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors.
Bioorg Med Chem Lett
; 20(22): 6739-43, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20855207
4.
Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity.
Microb Cell
; 3(3): 120-125, 2016 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28357342
5.
Quantitative proteomics reveals the mechanism and consequence of gliotoxin-mediated dysregulation of the methionine cycle in Aspergillus niger.
J Proteomics
; 131: 149-162, 2016 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26498071
6.
HIV cell fusion assay: phenotypic screening tool for the identification of HIV entry inhibitors via CXCR4.
J Biomol Screen
; 19(1): 108-18, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23989454
7.
In-vivo characterization of optical properties of pigmented skin lesions including melanoma using oblique incidence diffuse reflectance spectrometry.
J Biomed Opt
; 16(2): 020501, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21361657
8.
SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors.
Cancer Chemother Pharmacol
; 68(4): 923-33, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21298383
9.
Aurora kinase inhibitors based on the imidazo[1,2-a]pyrazine core: fluorine and deuterium incorporation improve oral absorption and exposure.
J Med Chem
; 54(1): 201-10, 2011 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21128646
10.
Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core.
ACS Med Chem Lett
; 1(5): 214-8, 2010 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900197