Detalhe da pesquisa
1.
CDKL5 kinase controls transcription-coupled responses to DNA damage.
EMBO J
; 40(23): e108271, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34605059
2.
DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC.
Cell
; 142(6): 930-42, 2010 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20850014
3.
RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health.
Mol Cell
; 66(5): 610-621.e4, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28575657
4.
Karyomegalic interstitial nephritis and DNA damage-induced polyploidy in Fan1 nuclease-defective knock-in mice.
Genes Dev
; 30(6): 639-44, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26980188
5.
K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin.
Mol Cell
; 58(1): 83-94, 2015 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25752573
6.
Differential roles and regulation of the protein kinases PAK4, PAK5 and PAK6 in melanoma cells.
Biochem J
; 479(16): 1709-1725, 2022 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35969127
7.
Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase.
EMBO J
; 37(24)2018 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30266825
8.
Allosteric mechanism for site-specific ubiquitination of FANCD2.
Nat Chem Biol
; 16(3): 291-301, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31873223
9.
An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells.
Biochem J
; 478(23): 4119-4136, 2021 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780645
10.
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms.
Biochem J
; 478(3): 553-578, 2021 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33459343
11.
Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases.
Mol Cell
; 52(2): 221-33, 2013 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24076219
12.
A complex comprising C15ORF41 and Codanin-1: the products of two genes mutated in congenital dyserythropoietic anaemia type I (CDA-I).
Biochem J
; 477(10): 1893-1905, 2020 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32239177
13.
PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72.
Biochem J
; 477(9): 1651-1668, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32227113
14.
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
Nat Immunol
; 9(9): 1028-36, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18690222
15.
mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival.
EMBO J
; 34(17): 2272-90, 2015 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26139536
16.
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
EMBO J
; 34(20): 2506-21, 2015 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26254304
17.
Publisher's Note: ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase.
J Cell Sci
; 135(6)2022 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35267011
18.
Identification of the MMS22L-TONSL complex that promotes homologous recombination.
Mol Cell
; 40(4): 632-44, 2010 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21055984
19.
Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.
Biochem J
; 474(4): 521-537, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27920213
20.
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.
EMBO J
; 32(7): 1008-22, 2013 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23463102