Detalhe da pesquisa
1.
RyR2 Serine-2030 PKA Site Governs Ca2+ Release Termination and Ca2+ Alternans.
Circ Res
; 132(2): e59-e77, 2023 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36583384
2.
Increased Ca2+ Transient Underlies RyR2-Related Left Ventricular Noncompaction.
Circ Res
; 133(2): 177-192, 2023 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37325910
3.
Modulation of cardiac ryanodine receptor 2 by calmodulin.
Nature
; 572(7769): 347-351, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31278385
4.
RyR2 C-terminal truncating variants identified in patients with arrhythmic phenotypes exert a dominant negative effect through formation of wildtype-truncation heteromers.
Biochem J
; 480(17): 1379-1395, 2023 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37492947
5.
Ca2+-CaM Dependent Inactivation of RyR2 Underlies Ca2+ Alternans in Intact Heart.
Circ Res
; 128(4): e63-e83, 2021 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375811
6.
RyR2 disease mutations at the C-terminal domain intersubunit interface alter closed-state stability and channel activation.
J Biol Chem
; 297(1): 100808, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34022226
7.
A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice.
J Cell Physiol
; 237(8): 3305-3316, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35621185
8.
The central domain of cardiac ryanodine receptor governs channel activation, regulation, and stability.
J Biol Chem
; 295(46): 15622-15635, 2020 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32878990
9.
Infanticide vs. inherited cardiac arrhythmias.
Europace
; 23(3): 441-450, 2021 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33200177
10.
The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca2+-ATPase, is a major determinant of Ca2+ alternans in intact mouse hearts.
J Biol Chem
; 293(35): 13650-13661, 2018 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29986885
11.
Differential deployment of sanctioning mechanisms by male and female host trees in a gynodioecious fig-wasp mutualism.
Ecology
; 100(3): e02597, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30615203
12.
Pathogenic mechanism of a catecholaminergic polymorphic ventricular tachycardia causing-mutation in cardiac calcium release channel RyR2.
J Mol Cell Cardiol
; 117: 26-35, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29477366
13.
The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor.
J Biol Chem
; 292(4): 1385-1395, 2017 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27927985
14.
Reduced threshold for store overload-induced Ca2+ release is a common defect of RyR1 mutations associated with malignant hyperthermia and central core disease.
Biochem J
; 474(16): 2749-2761, 2017 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28687594
15.
The EF-hand Ca2+ Binding Domain Is Not Required for Cytosolic Ca2+ Activation of the Cardiac Ryanodine Receptor.
J Biol Chem
; 291(5): 2150-60, 2016 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26663082
16.
The Cytoplasmic Region of Inner Helix S6 Is an Important Determinant of Cardiac Ryanodine Receptor Channel Gating.
J Biol Chem
; 291(50): 26024-26034, 2016 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27789712
17.
Enhanced Cytosolic Ca2+ Activation Underlies a Common Defect of Central Domain Cardiac Ryanodine Receptor Mutations Linked to Arrhythmias.
J Biol Chem
; 291(47): 24528-24537, 2016 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27733687
18.
Costimulation of soil glycosidase activity and soil respiration by nitrogen addition.
Glob Chang Biol
; 23(3): 1328-1337, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27362835
19.
Suppression of ryanodine receptor function prolongs Ca2+ release refractoriness and promotes cardiac alternans in intact hearts.
Biochem J
; 473(21): 3951-3964, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27582498
20.
A novel RYR2 loss-of-function mutation (I4855M) is associated with left ventricular non-compaction and atypical catecholaminergic polymorphic ventricular tachycardia.
J Electrocardiol
; 50(2): 227-233, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27646203