Mind the gap: Increased inter-letter spacing as a means of improving reading performance.

Theeffects of text display, specificallywithin-word spacing, on children's reading at different developmental levels has barely been investigated.This study explored the influence of manipulating inter-letter spacing on reading performance (accuracy and rate) of beginner Hebrew readers compared with older readers and of low-achieving readers compared with age-matched high-achieving readers.A computer-based isolated word reading task was performed by 132 first and third graders. Words were displayed under two spacing conditions: standard spacing (100%) and increased spacing (150%). Words were balanced for length and frequency across conditions. Results indicated that increased spacing contributed to reading accuracy without affecting reading rate. Interestingly, all first graders benefitted fromthe spaced condition. Thiseffect was found only in long words but not in short words. Among third graders, only low-achieving readers gained in accuracy fromthespaced condition. Thetheoretical and clinical effects ofthefindings are discussed.

When left-hemisphere reading is compromised: Comparing reading ability in participants after left cerebral hemispherectomy and participants with developmental dyslexia.

OBJECTIVE: We investigated reading skills in individuals who have undergone left cerebral hemispherectomy and in readers with developmental dyslexia to understand diverse characteristics contributing to reading difficulty. Although dyslexia is a developmental disorder, left hemispherectomy requires that patients (re)establish the language process needed to perform the language-based tasks in the nondominant (right) hemisphere to become readers. METHODS: Participants with developmental dyslexia (DD; n = 11) and participants who had undergone left hemispherectomy (HEMI; n = 11) were matched on age and gender, and were compared on timed and untimed measures of single word and pseudo-word reading. The hemispherectomy group was subdivided into prenatal (in utero) and postnatal (>3 years) insult groups, indicating the timing of the primary lesion that ultimately required surgical intervention. RESULTS: On an untimed reading measure, the readers with DD were comparable to individuals who had undergone left hemispherectomy due to prenatal insult, but both scored higher than the postnatal hemispherectomy group. Timed word reading differed across groups. The hemispherectomy prenatal subgroup had low average scores on both timed and untimed tests. The group with dyslexia had average scores on untimed measures and below average scores on timed reading. The hemispherectomy postnatal group had the lowest scores among the groups by a significant margin, and the most pronounced reading difficulty. SIGNIFICANCE: Patients with prenatal lesions leading to an isolated right hemisphere (RH) have the potential to develop reading to a degree comparable to that in persons with dyslexia for single word reading. This potential sharply diminishes in individuals who undergo hemispherectomy due to postnatal insult. The higher scores of the prenatal hemispherectomy group on timed reading suggest that under these conditions, individuals with an isolated RH can compensate to a significant degree.

Calibration of Self-Reports of Anxiety and Physiological Measures of Anxiety While Reading in Adults With and Without Reading Disability.

Reading difficulty has been linked to anxiety in adults yet and has not been systematically studied especially in compensated adults with dyslexia. This study examined the relationships between anxiety ratings and physiological arousal while reading among adults with reading disability (RD) compared to skilled readers (SR). Nineteen compensated adults with RD and 20 SR adults were administered a battery of reading tasks and anxiety self-report questionnaires. Physiological measures of arousal were recorded during text reading task. Adults with RD scored significantly lower than SR on all cognitive and reading related measures. They showed no differences on any of the self-report anxiety measures. Interestingly, in the skilled readers' sample, physiological arousal while reading correlated with trait anxiety. No correlations between physiological and self-reported data were found in the RD sample. These findings suggest a model of resiliency in compensated adults with reading disabilities that includes lower anxiety levels and a discord between anxiety reports and actual arousal rates. Copyright © 2016 John Wiley & Sons, Ltd.

Many ways to read your vowels--Neural processing of diacritics and vowel letters in Hebrew.

The current study examined the effect of orthographic transparency and familiarity on brain mechanisms involved in word recognition in adult Hebrew readers. We compared the effects of diacritics that provide transparent but less familiar information and vowel letters that increase orthographic transparency without compromising familiarity. Brain activation was measured in 18 adults during oral reading of single words, while manipulating the presence of diacritic marks, the presence of a vowel letter, and word length (3 vs. 4 consonants). We found opposite effects of diacritics and vowel letters on temporo-parietal regions associated with mapping orthography to phonology. The increase in activation for diacritic marks and the decrease in activation for vowel letters in these regions suggest that the greater familiarity of vowel letters compared to diacritics overrides the effect of orthographic transparency. Vowel letters also reduced activation in regions associated with semantic processing in unpointed words, and were thus distinct from the effect of an additional consonant. Altogether the results suggest that both orthographic transparency and familiarity contribute to word recognition.

Integration of gray matter nodules into functional cortical circuits in periventricular heterotopia.

Alterations in neuronal circuitry are recognized as an important substrate of many neurological disorders, including epilepsy. Patients with the developmental brain malformation of periventricular nodular heterotopia (PNH) often have both seizures and dyslexia, and there is evidence to suggest that aberrant neuronal connectivity underlies both of these clinical features. We used task-based functional MRI (fMRI) to determine whether heterotopic nodules of gray matter in this condition are integrated into functional cortical circuits. Blood oxygenation level-dependent (BOLD) fMRI was acquired in eight participants with PNH during the performance of reading-related tasks. Evidence of neural activation within heterotopic gray matter was identified, and regions of cortical coactivation were then mapped systematically. Findings were correlated with resting-state functional connectivity results and with performance on the fMRI reading-related tasks. Six participants (75%) demonstrated activation within at least one region of gray matter heterotopia. Cortical areas directly overlying the heterotopia were usually coactivated (60%), as were areas known to have functional connectivity to the heterotopia in the task-free resting state (73%). Six of seven (86%) primary task contrasts resulted in heterotopia activation in at least one participant. Activation was most commonly seen during rapid naming of visual stimuli, a characteristic impairment in this patient population. Our findings represent a systematic demonstration that heterotopic gray matter can be metabolically coactivated in a neuronal migration disorder associated with epilepsy and dyslexia. Gray matter nodules were most commonly coactivated with the anatomically overlying cortex and other regions with resting-state connectivity to heterotopia. These results have broader implications for understanding the network pathogenesis of both seizures and reading disabilities.

Filamin A mutation associated with normal reading skills and dyslexia in a family with periventricular heterotopia.

Periventricular heterotopia (PH) is a disorder of neuronal migration during fetal development that is characterized by morphologically normal neurons being located in an anatomically abnormal position in the mature brain. PH is usually diagnosed in patients presenting with a seizure disorder, when neuroimaging demonstrates the ectopically placed nodules of neurons. PH is a genetically and phenotypically heterogeneous disorder. The most commonly identified genetic cause is the X-linked dominant inheritance of mutations in the Filamin A (FLNA) gene. Multiple lines of evidence support the contribution of genetic factors in dyslexia. As dyslexia does not show a single-gene pattern of inheritance, it is classified as a complex genetic disorder. We have recently identified a specific reading fluency deficit in a variable group of patients with PH, in the context of normal intelligence. Here, we present a study of a mother-daughter pair who share bilateral widespread gray matter heterotopia caused by a novel mutation in FLNA and the same pattern of X-chromosome inactivation but who exhibit divergent reading and cognitive profiles. This novel observation highlights the uncertainty of using heterotopia anatomy in clinical practice to predict behavioral outcome.

Abnormal structural and functional brain connectivity in gray matter heterotopia.

PURPOSE: Periventricular nodular heterotopia (PNH) is a malformation of cortical development associated with epilepsy and dyslexia. Evidence suggests that heterotopic gray matter can be functional in brain malformations and that connectivity abnormalities may be important in these disorders. We hypothesized that nodular heterotopia develop abnormal connections and systematically investigated the structural and functional connectivity of heterotopia in patients with PNH. METHODS: Eleven patients were studied using diffusion tensor tractography and resting-state functional connectivity MRI with bold oxygenation level-dependent (BOLD) imaging. Fiber tracks with a terminus within heterotopic nodules were visualized to determine structural connectivity, and brain regions demonstrating resting-state functional correlations to heterotopic nodules were analyzed. Relationships between these connectivity results and measures of clinical epilepsy and cognitive disability were examined. KEY FINDINGS: A majority of heterotopia (69%) showed structural connectivity to discrete regions of overlying cortex, and almost all (96%) showed functional connectivity to these regions (mean peak correlation coefficient 0.61). Heterotopia also demonstrated connectivity to regions of contralateral cortex, other heterotopic nodules, ipsilateral but nonoverlying cortex, and deep gray matter structures or the cerebellum. Patients with the longest durations of epilepsy had a higher degree of abnormal functional connectivity (p = 0.036). SIGNIFICANCE: Most heterotopic nodules in PNH are structurally and functionally connected to overlying cortex, and the strength of abnormal connectivity is higher among patients with the longest duration of epilepsy. Along with prior evidence that cortico-cortical tract defects underlie dyslexia in this disorder, the current findings suggest that altered connectivity is likely a critical substrate for neurologic dysfunction in brain malformations.

Neural Processing of Morphology During Reading in Children.

The importance of morphological segmentation for reading has been shown in numerous behavioral studies in children and adults. However, little is known about developmental changes in the neural basis of morphological processing. In addition to effects of age and reading skill, morphological processing during reading may be affected by the morphological structure of the language and the transparency of its orthography. Hebrew provides a unique opportunity to study these factors, with its rich morphological structure, and two versions of script that differ in orthographic transparency. Two groups of children (2nd-3rd and 5th-6th graders) were scanned using fMRI while reading aloud Hebrew nouns. Half of the words were composed of roots and templates (bi-morphemic) and half were mono-morphemic. The words were presented at two levels of transparency: with or without diacritics. ROI analyses showed greater activation for mono over bi-morphemic words across groups in the anterior portions of bilateral middle and superior temporal gyri, especially for the transparent script. These results diverge from a previous finding in adults, showing left frontal activation in the non-transparent script with the same stimuli. These results support the early sensitivity of young Hebrew readers to the rich morphological structure of their language but suggest a developmental change in the role of morphological processes during reading. While in adults morpho-phonological segmentation during reading may compensate for orthographic opacity, morphological processes in children may rely more on semantic aspects, and are enhanced by orthographic transparency.

Start shallow and grow deep: The development of a Hebrew reading brain.

Brain plasticity implies that readers of different orthographies can have different reading networks. Theoretical models suggest that reading acquisition in transparent orthographies relies on mapping smaller orthographic units to phonology, than reading opaque orthographies; but what are the neural mechanisms underlying this difference? Hebrew has a transparent (pointed) script used for beginners, and a non-transparent script used for skilled readers. The current study examined the developmental changes in brain regions associated with phonological and orthographic processes during reading pointed and un-pointed words. Our results highlight some changes that are universal in reading development, such as a developmental increase in frontal involvement (in bilateral inferior frontal gyrus (IFG) pars opercularis), and increase in left asymmetry (in IFG pars opercularis and superior temporal gyrus, STG) of the reading network. Our results also showed a developmental increase in activation in STG, which stands in contrast to previous studies in other orthographies. We further found an interaction of word length and diacritics in bilateral STG and the visual word form area (VWFA) across both groups. These findings suggest that children slightly adjust their reading depending on orthographic transparency, relying on smaller units when reading a transparent script and on larger units when reading an opaque script. Our results also showed that phonological abilities across groups correlated with activation in the VWFA, regardless of transparency, supporting the continued role of phonology at all levels of orthographic transparency. Our findings are consistent with multiple route reading models, in which both phonological and orthographic processing of multiple size units continue to play a role in children's reading of transparent and opaque scripts during reading development. The results further demonstrate the importance of taking into account differences between orthographies when constructing neural models of reading acquisition.

Accelerating reading via local priming.

Visual nonlinguistic local and global priming can change one's state of mind and influence other upcoming tasks. Reading involves both detailed and higher-level global processing. Little is known about the effects of visual non-linguistic priming on lower level processing of words, as well as about the potentially higher-level processing of written information. In two experiments, the effects of global versus local priming on single word reading (Experiment 1) as well as text reading (Experiment 2) were investigated in adults. The results revealed facilitation effects of local priming on single word reading as well as on text reading rate, with no impairment of reading accuracy and comprehension. These novel results are further interpreted within different cognitive and neurological frameworks. In addition, clinical and research implications for the local/global attention and reading domain are discussed.

Morphological decomposition compensates for imperfections in phonological decoding. Neural evidence from typical and dyslexic readers of an opaque orthography.

The current study examined the widely held, but un-tested, assumption that morphological decomposition can compensate for missing phonological information in reading opaque orthographies. In addition, we tested whether morphological decomposition can compensate for the phonological decoding deficits in readers with dyslexia. Hebrew provides a unique opportunity to test these questions as it has a rich Semitic morphology, and two versions of script: a transparent orthography (with diacritic marks, 'pointed') and an opaque orthography (without diacritic marks, 'un-pointed'). In two experiments, one behavioral and one fMRI, skilled and dyslexic readers read aloud Hebrew nouns: half bi-morphemic (root + pattern) and half mono-morphemic (non-decomposable). Each word was presented both in the transparent orthography (pointed), and in the opaque orthography (un-pointed). While skilled readers were faster, and showed no effects of diacritics or morphology, dyslexic readers read pointed words more slowly than un-pointed words and bi-morphemic words faster than mono-morphemic words. The imaging results showed: 1) In both groups a morphological effect was found in un-pointed words, in left inferior and middle frontal gyri, associated with morpho-phonological decomposition. 2) Only readers with dyslexia showed a morphological effect in pointed words in the left occipito-temporal cortex, associated with orthographic processing. 3) Dyslexic readers also showed a positive association between morphological awareness and activation in the left occipito-temporal cortex during reading of all words, and activation in inferior frontal cortex during reading of un-pointed bi-morphemic words. Altogether, these findings suggest that in both typical and dyslexic readers morphological decomposition can compensate for the missing phonological information in an opaque orthography. The results also show that readers with dyslexia can rely on morphological decomposition to compensate for their deficits in phonological decoding. Finally, these results highlight the way in which unique language specific properties shape the neural mechanisms underlying typical and atypical reading.

Gray matter volumes and cognitive ability in the epileptogenic brain malformation of periventricular nodular heterotopia.

Periventricular nodular heterotopia (PNH) is a brain malformation clinically characterized by the triad of epilepsy, normal intelligence, and dyslexia. We investigated the structure-function relationship between cerebral volumes and cognitive ability in this disorder by studying 12 subjects with PNH and 6 controls using volumetric analysis of high-resolution anatomical MRI and neuropsychological testing. Total cerebral volumes and specific brain compartment volumes (gray matter, white matter, and cerebrospinal fluid) in subjects with PNH were comparable to those in controls. There was a negative correlation between heterotopic gray matter volume and cortical gray matter volume. Cerebral and cortical volumes in PNH did not correlate with Full Scale IQ, unlike in normal individuals. Our findings support the idea that heterotopic nodules contain misplaced neurons that would normally have migrated to the cortex, and suggest that structural correlates of normal cognitive ability may be different in the setting of neuronal migration failure.

Theory and reported practice in EFL literacy instruction: EFL teachers' perceptions about classroom practices.

Acquiring literacy in English as a foreign language (EFL) is important for language development. However, many students enter middle school without adequate EFL literacy skills. This may indicate a gap between EFL literacy instruction theory and the classroom practice that is occurring in elementary school classrooms. The aim of this study was to explore the components of EFL literacy instruction as perceived by teachers. The study investigated whether perceptions of classroom practices are theoretically based, thus shedding light on the gap between EFL literacy theory and practice. The participants were 167 EFL elementary school teachers, who submitted anonymous online questionnaires regarding their reported EFL teaching in year one, two, three, four, and five of elementary school. The research was based on the five pillars of literacy instruction for English as a first language (National Reading Panel, 2000) and additional EFL components (August & Shanahan, 2006). Results of this study showed that EFL teachers expressed views that may indicate a gap between teachers' practices and most cutting-edge research. The study concluded that providing EFL elementary school teachers with theoretical knowledge may lead to more productive literacy programs and may improve classroom practices.

The varieties of pathways to dysfluent reading: comparing subtypes of children with dyslexia at letter, word, and connected text levels of reading.

The majority of work on the double-deficit hypothesis (DDH) of dyslexia has been done at the letter and word levels of reading. Key research questions addressed in this study are (a) do readers with different subtypes of dyslexia display differences in fluency at particular reading levels (e.g., letter, word, and connected text)? and (b) do children with dyslexia identified by either low-achievement or ability-achievement discrepancy criteria show similar differences when classified by the DDH? To address these questions, the authors assessed a sample of 158 children with severe reading impairments in second and third grades on an extensive battery and classified them into three reader subtypes using the DDH. The results demonstrated that the three DDH subtypes exhibited differences in fluency at different levels of reading (letter, word, and connected text), underscoring the separate reading profiles of these subtypes and the different possible routes to dysfluency in reading disabilities. Furthermore, the results suggest that the different patterns among DDH subtypes are primarily driven by the ability-achievement discrepancy group. The implications of these findings are discussed for intervention, reading theory, and a more refined understanding of heterogeneity.

Measuring Multiple Text Integration: A Review.

Multiple text integration is an important skill in modern society, required in heterogeneous situations, across many disciplines and in daily life. It is a complex skill that builds on bottom-up and top-down processes (Britt and Rouet, 2012). As a complex skill it has been measured in the literature using different techniques. To date, the different ways in which researchers have defined and operationalized the term have not been reviewed. Therefore, the aim of this paper is to review how multiple text integration has been theoretically and empirically assessed. The current paper reviews which texts were typically used, which aspects of integration were assessed, and with which scoring rubrics. Finally, we propose that despite the diverse use of tasks, important features of multiple text integration are missing from current research.

The Effect of Font Size on Children's Memory and Metamemory.

Recently, there has been a growing interest in the effect of perceptual features of learning materials on adults' memory and metamemory. Previous studies consistently have found that adults use font size as a cue when monitoring their learning, judging that they will remember large font size words better than small font size words. Most studies have not demonstrated a significant effect of font size on adults' memory, but a recent meta-analysis of these studies revealed a subtle memory advantage for large font words. The current study extended this investigation to elementary school children. First and fifth-sixth graders studied words for a free recall test presented in either large or small font and made judgments of learning (JOLs) for each word. As did adults, children predicted they would remember large font size words better than small font size words and, in fact, actually remembered the large font size words better. No differences were observed between the two age groups in the effect of font size on memory or metamemory. These results suggest that the use of font size as a cue when monitoring one's own learning is robust across the life span and, further, that this cue has at least some validity.

Predictive Models of Word Reading Fluency in Hebrew.

This study examined a multi-componential approach to reading fluency in first and third grade Hebrew speaking children. Measures of naming speed, phonological awareness (PA), morphological awareness (MA), syntax awareness, and vocabulary were administered to first (N = 68) and third (N = 67) graders. Hierarchical regression models revealed that in both grades, naming speed accounted for most of the variance in each model. However, while in the first grade, word reading fluency was also predicted by vocabulary, in the third grade, both PA and MA were significant additional predictors. Predictive models of word reading fluency in Hebrew and applied implications are proposed.

Reading Self-Concept and Reading Anxiety in Second Grade Children: The Roles of Word Reading, Emergent Literacy Skills, Working Memory and Gender.

Background: Most studies in the field of reading have focused on the linguistic and cognitive factors. Less is known about the affective aspects of reading in young readers, such as self-perceptions of reading, and reading anxiety. Aims: This study aimed to shed light on the direct and indirect relations between reading and related skills (working memory, emergent literacy skills, word reading accuracy and rate, and gender) as sources of reading affect (reading self-concept and anxiety). Sample: A total of 115 Hebrew speaking second graders participated in this study. Methods: A set of measures assessing reading accuracy and rate, emergent literacy skills (phonological fluency, rapid automatized naming and working memory) and reading affect questionnaires (reading self-concept and reading anxiety) were administered to the participants. Results: Path analysis was used as the primary analytic approach. Results indicated a negative moderate relation between reading self-concept and reading anxiety. The relations of working memory and emergent literacy to reading self-concept and reading anxiety were indirect via word reading accuracy and reading rate. Girls reported higher reading anxiety and lower reading self-concept, despite higher performance in reading accuracy and no difference in reading rate. Conclusion: The current results support the importance of examining reading affect and potential sources of reading affect. Results suggest that reading self-concept and reading anxiety and their related skills should be considered in designing reading intervention and instructions.

Orthographic Transparency Enhances Morphological Segmentation in Children Reading Hebrew Words.

Morphological processing of derived words develops simultaneously with reading acquisition. However, the reader's engagement in morphological segmentation may depend on the language morphological richness and orthographic transparency, and the readers' reading skills. The current study tested the common idea that morphological segmentation is enhanced in non-transparent orthographies to compensate for the absence of phonological information. Hebrew's rich morphology and the dual version of the Hebrew script (with and without diacritic marks) provides an opportunity to study the interaction of orthographic transparency and morphological segmentation on the development of reading skills in a within-language design. Hebrew speaking 2nd (N = 27) and 5th (N = 29) grade children read aloud 96 noun words. Half of the words were simple mono-morphemic words and half were bi-morphemic derivations composed of a productive root and a morphemic pattern. In each list half of the words were presented in the transparent version of the script (with diacritic marks), and half in the non-transparent version (without diacritic marks). Our results show that in both groups, derived bi-morphemic words were identified more accurately than mono-morphemic words, but only for the transparent, pointed, script. For the un-pointed script the reverse was found, namely, that bi-morphemic words were read less accurately than mono-morphemic words, especially in second grade. Second grade children also read mono-morphemic words faster than bi-morphemic words. Finally, correlations with a standardized measure of morphological awareness were found only for second grade children, and only in bi-morphemic words. These results, showing greater morphological effects in second grade compared to fifth grade children suggest that for children raised in a language with a rich morphology, common and easily segmented morphemic units may be more beneficial for younger compared to older readers. Moreover, in contrast to the common hypothesis, our results show that morphemic segmentation does not compensate for the missing phonological information in a non-transparent orthography, but rather that morphological segmentation is most beneficial in the highly transparent script. These results are consistent with the idea that morphological and phonological segmentation processes occur simultaneously and do not constitute alternative pathways to visual word recognition.

Reading fluency: the whole is more than the parts.

This study examined the relative contributions of phonological awareness, orthographic pattern recognition, and rapid letter naming to fluent word and connected-text reading within a dyslexic sample of 123 children in second and third grades. Participants were assessed on a variety of fluency measures and reading subskills. Correlations and hierarchical multiple regression analyses were carried out to explore these relationships. The results demonstrate that phonological awareness, rapid letter naming, and orthographic pattern recognition contribute to word-reading skills. Furthermore, rapid naming, orthographic pattern recognition, and word reading fluency moderately predict different dimensions of connected-text reading (i.e., rate, accuracy, and comprehension) whereas phonological awareness contributes only to the comprehension dimension of connected-text reading. The findings support the multidimensional nature of fluency in which the whole is more than its parts.